中国免疫学杂志2024，Vol.40Issue(4)：857-861,5.DOI:10.3969/j.issn.1000-484X.2024.04.031
SARS-CoV-2 S蛋白主要结构与突变及S蛋白引起疾病的潜在机制
Min structure and mutation of SARS-CoV-2 S protein and potential mechanism of S protein-induced disease
摘要
Abstract
SARS-CoV-2 caused severe threat to people's health all over the world,and has attracted widespread attention from researchers.The spike protein of SARS-CoV-2 is a key structure mediating the binding of the virus to its host.Therefore,it is im-portant to elucidate the mechanism of spike protein-induced immune responses.We've reviewed the structure of spike protein from al-pha to omicron variant,as well as the potential mechanisms of spike-induced in multiple systems,so as to provide a reference for dis-ease prevention and treatment.关键词
SARS-CoV-2 S蛋白/ACE2/呼吸道炎症Key words
SARS-CoV-2 S protein/ACE2/Airway inflammation分类
医药卫生引用本文复制引用
刘兴健,张锐钢..SARS-CoV-2 S蛋白主要结构与突变及S蛋白引起疾病的潜在机制[J].中国免疫学杂志,2024,40(4):857-861,5.基金项目
国家自然科学基金(82000008) （82000008）
广东省基础与应用基础研究基金区域联合基金(2019A1515110126). （2019A1515110126）
