中国实用外科杂志2024，Vol.44Issue(4)：447-451,5.DOI:10.19538/j.cjps.issn1005-2208.2024.04.16
生物补片与合成补片用于腹腔镜食管裂孔疝修补术短期临床疗效及安全性比较:一项多中心对照研究
Comparison of short-term clinical efficacy and safety between biological and synthetic meshesin:a multicenter controlled study
摘要
Abstract
Objective To compare the short-term clinical efficacy and safety of biological versus synthetic meshes in laparoscopic esophageal hiatal hernia repair.Methods This multicenter controlled clinical trial involved 298 patients undergoing laparoscopic esophageal hiatal hernia repair from January 2020 to December 2022 in six centers,led by Beijing Chaoyang Hospital,Capital Medical University.Participants were divided into either the biological mesh group or the synthetic mesh group,with 149 patients in each.Follow-up data were collected at 6 and 12 months postoperatively via phone or clinic visits.Results No significant difference was observed in the recurrence rates at 12 months postoperatively between the two groups,with 2.2％(3/135)in the biological mesh group and 2.9％(4/137)in the synthetic mesh group(P=0.716).Additionally,no complications were observed during the follow-up period in either group.Regarding symptom improvement,preoperative symptom scores comparison showed no significant differences between the biological and synthetic patch groups in terms of burning sensation behind the sternum,acid reflux,belching,chest pain,early satiety,,and dysphagia(P＞0.05).Similarly,there was no significant difference in symptom improvement scores at 12 months post-surgery between the two groups(P＞0.05).Furthermore,comparisons of quality of life scores,including physical functioning,role physical,bodily pain,general health,vitality,social functioning,role emotional,mental health,and health change,before and 12 months after surgery,revealed no significant differences between the groups(P＞0.05).Conclusion In laparoscopic hiatal hernia repair,biological and synthetic meshes exhibit similar short-term recurrence rates,symptom improvement,and quality of life enhancements.关键词
食管裂孔疝/腹腔镜/生物补片/合成补片/临床疗效/安全性Key words
esophageal hiatal hernia/laparoscopy/biological mesh/synthetic mesh/clinical efficacy/safety分类
医药卫生引用本文复制引用
杜华栋,辛城霖,罗颖,杜兴,李若凡,任书林,伍冀湘,田广健,刘殿刚,尹杰,吴继敏,刘小莉,杨慧琪,聂玉胜,胡志伟,马秋月,关磊,赵敏娴,李海云,马松松..生物补片与合成补片用于腹腔镜食管裂孔疝修补术短期临床疗效及安全性比较:一项多中心对照研究[J].中国实用外科杂志,2024,44(4):447-451,5.基金项目
北京市卫生健康委员会首都卫生发展科研专项(自主创新)资助(No.首发2020-2-2035) （自主创新）
