中国实用外科杂志2024，Vol.44Issue(4)：467-472,6.DOI:10.19538/j.cjps.issn1005-2208.2024.04.20
肝动脉栓塞联合延期腹腔镜肝切除治疗巨大肝血管瘤临床疗效分析
Clinical application of transcatheter arterial embolization followed by laparoscopic hepatectomy for giant hepatic hemangioma
摘要
Abstract
Objective To explore the feasibility of transcatheter arterial embolization(TAE)followed by laparoscopic hepatectomy in the treatment of giant hepatic hemangioma.Methods Forty-two patients with giant hepatic hemangioma who had been hospitalized during the period from January 2022 to November 2023 in our center were analyzed.According to different treatment methods,they were divided into two groups,whereby 19 cases in the delayed surgery group were treated with TAE and delayed laparoscopic hepatectomy,while 23 cases in the one-stage surgery group were treated with laparoscopic hepatectomy.The tumor diameters before laparoscopic surgery or TAE,the operation characteristics,and short-term complications of the two groups were compared and analyzed.Results After TAE treatment,the tumor diameters of the delayed surgery group were significantly decreased((15.1±3.0)cm vs.(11.2± 2.5)cm,P＜0.001).The operation time(240(180-270)min vs.300(240-360)min,P=0.035),intraoperative blood loss(100(80-100)mL vs.180(100-400)mL,P=0.024),and the postoperative hospital stay(7(5-8)d vs.8(7-9)d,P=0.049)in the delayed surgery group were significantly lower than in the one-stage surgery group.The postoperative serum levels of the hepatic function index were not statistically different between the two groups.There was no significant difference in the incidence of Clavien-Dindo complications and postoperative complications.Conclusion Transcatheter arterial embolization followed by laparoscopic hepatectomy in the treatment of giant hepatic hemangioma is not only safe and effective,but can also promote the early discharge of patients and simplify the operative procedures,which provides a new train of thought for the treatment of giant hepatic hemangioma.关键词
肝血管瘤/肝动脉栓塞/腹腔镜肝切除术/可视化技术Key words
giant hepatic hemangioma/transcatheter arterial chemoembolization/laparoscopic hepatectomy/visualization techniques分类
医药卫生引用本文复制引用
李馨慈,曾小军,陈洪彬,陶海粟,祝文,杨剑..肝动脉栓塞联合延期腹腔镜肝切除治疗巨大肝血管瘤临床疗效分析[J].中国实用外科杂志,2024,44(4):467-472,6.基金项目
国家自然科学基金项目(No.82272132) （No.82272132）
广东省基础与应用基础研究基金项目(No.2021A1515011869) （No.2021A1515011869）
广东省基础与应用基础研究基金粤港澳研究团队项目(No.2021B1515130003) （No.2021B1515130003）
中国博士后科学基金项目(No.2022M721514) （No.2022M721514）
广州市重点研发计划项目(No.2023B03J1246) （No.2023B03J1246）
