中国医院用药评价与分析2024，Vol.24Issue(4)：408-411,416,5.DOI:10.14009/j.issn.1672-2124.2024.04.005
安胎经典名方寿胎丸的古今文献分析与关键信息考证
Historical Evolution and Textual Research on Classical Prescription Shoutai Pills for Fetus Protection
摘要
Abstract
OBJECTIVE:To systematically collate the ancient and modern literature of the classic prescription Shoutai pills,and to research the key information of Shoutai pills,so as to provide scientific basis for its clinical application and preparation research and development.METHODS:Based on ancient and modern literature,the historical origin,composition,dosage,processing,preparation,decocting method,efficacy and application of classic prescription Shoutai pills were analyzed by modern metrology.RESULTS:Through literature search,a total of 1 ancient literature and 151 modern clinical studies were collected.Shoutai pills were made of fried Cuscuta australis,Herba Taxilli,Dipsacus asperoides and Asini Corii Colla.According to the ancient and modern dosage conversion,Cuscuta australis 149.2 g,Herba Taxilli 74.6 g,Dipsacus asperoides 74.6 g and Asini Corii Colla 74.6 g(quality of Cuscuta australis ∶Herba Taxilli ∶ Dipsacus asperoides ∶ Asini Corii Colla = 2 ∶ 1 ∶ 1 ∶ 1).The first three kinds of medicine were made into the finest powder and made into pills with hydrated Ejiao.Each pill was about 0.37 g,20 pills were taken each time,twice a day in the morning and afternoon.Ancient records showed that the main treatment of Shoutai pills was"miscarriage",and in modern clinical practice,Shoutai pills were mainly used for recurrent miscarriage and preterm miscarriage.Shoutai pills played a protective role in pregnancy mainly by reducing embryo loss,promoting endometrial demembranization,regulating autophagy and inhibiting apoptosis.The main active components of Shoutai pills were flavonoids,organic acids,triterpenoid saponins,iridoid glycosides and lactones.CONCLUSIONS:Historical evolution and textual research on classical prescription Shoutai pills for fetus protection provide reference basis for the later development of the prescription.关键词
安胎/经典名方/寿胎丸/文献考证Key words
Fetus protection/Classical prescription/Shoutai pills/Textual research分类
药学引用本文复制引用
贡磊磊,高宏杰,李心蕾,赵涵,张雪艳,冯欣..安胎经典名方寿胎丸的古今文献分析与关键信息考证[J].中国医院用药评价与分析,2024,24(4):408-411,416,5.基金项目
国家自然科学基金青年项目(No.82204698) （No.82204698）
北京市属医院科研培育计划项目(No.PZ2023029) （No.PZ2023029）
