中国中西医结合影像学杂志2024，Vol.22Issue(3)：262-266,277,6.DOI:10.3969/j.issn.1672-0512.2024.03.004
基于CT的影像组学对胃癌不同站点正常大小淋巴结转移的预测价值
Prediction of normal-sized lymph node metastasis at different sites of gastric cancer based on CT radiomics
摘要
Abstract
Objective:To investigate the predictive value of CT-based radiomics in the prediction of normal-sized lymph node metastasis at different sites of gastric cancer.Methods:A retrospective analysis was performed for 303 normal-sized lymph nodes in 233 patients with gastric cancer that met the inclusion criteria,and the lymph nodes were divided into two zones,Zone 1(the first station lymphnode,175 lymph nodes)and Zone 2(the second and third station lymphnode,128 lymph nodes),and the lymph nodes of the two zones were divided into the training and validation cohorts at a ratio of 7∶3,respectively.The clinical-imaging combination model was constructed for the lymph nodes in the two zones,by screening the clinical independent risk factors and radiomics characteristics,and using four different classifiers,decision tree,LinearSVC,SVM and logistic regression.The performance of the combination model was evaluated by AUC,and the clinical value of the model was analyzed by DCA.Results:Four clinical-imaging combination models were established in the two zones,and the SVM model of Zone 1 showed the best discrimination performance with the AUCs of 0.960(95%CI 0.925～0.995)and 0.731(95%CI 0.556～0.905)in the training and validation cohorts,respectively.The SVM model of Zone 2 also showed the best discrimination performance with the AUCs of 0.998(95%CI 0.993～1.000)and 0.959(95%CI 0.924～0.994)in the training and validation cohorts,respectively.DCA showed that the application of the SVM combination models of the two zones in clinical decision-making achieved great benefits.Conclusion:The clinical-imaging combination model based on CT radiomics can predict the normal-sized lymph node metastasis at different sites of gastric cancer before surgery.关键词
胃肿瘤/正常大小淋巴结转移/影像组学/术前预测/体层摄影术,X线计算机Key words
Stomach neoplasms/Normal-sized lymph node metastasis/Radiomics/Preoperative prediction/Tomography,X-ray computed引用本文复制引用
马雯雯,蒋常琴,冯强,徐芹艳,张文轩,范振,姬国敏,王锡臻..基于CT的影像组学对胃癌不同站点正常大小淋巴结转移的预测价值[J].中国中西医结合影像学杂志,2024,22(3):262-266,277,6.基金项目
潍坊市卫生健康委员会科研项目(WFWSJK-2023-037) （WFWSJK-2023-037）
河北省卫生健康委医学科学研究项目(20211406). （20211406）
