中国中西医结合影像学杂志2024，Vol.22Issue(3)：338-341,364,5.DOI:10.3969/j.issn.1672-0512.2024.03.020
双能量CT评估不同Child-Pugh分级肝硬化肝脾血流动力学的初步研究
A preliminary study of dual-energy CT in evaluation for hepatic and splenic hemodynamic parameters in cirrhosis with different Child-Pugh classification
摘要
Abstract
Objective:To investigate the changes of hepatic and splenic hemodynamic parameters and their correlation with the Child-Pugh classification using dual-energy CT iodine image.Methods:Arterial and portal venous phase iodine maps of 48 cirrhotic patients(the cirrhotic group)and 23 control individuals(the control group)were retrieved to measure six parameters:iodine concentration in arterial phase(Ia),iodine concentration in portal venous phase(Ip),portal venous iodine concentration(PVIC),arterial iodine fraction(AIF),splenic iodine concentration in arterial phase(SIa)and splenic iodine concentration in portal venous phase(SIp).48 patients were divided into three subgroups,Child-Pugh A subgroup(27 cases),Child-Pugh B subgroup(14 cases),and Child-Pugh C subgroup(7 cases).One-way ANOVA was used for multiple groups comparisons,and Spearman correlation was used for two-variable correlations.Results:There were significant differences in all six parameters among the four groups(all P<0.001),Ia,AIF and SIa in Child-Pugh A,B,C subgroups were higher than those in the control group(all P<0.05)and Ip and PVIC were lower(all P<0.05).Ia,AIF,SIa and SIp in the cirrhosis group were positively correlated with the Child-Pugh classification(all P<0.05),while Ip and PVIC were negatively correlated(both P<0.05).Conclusions:The hepatic and splenic hemodynamic parameters in cirrhosis patients have differences with those in healthy people.The hepatic and splenic hemodynamic parameters in cirrhosis patients are correlated with the Child-Pugh classification.Dual-energy CT can be used to explore the hemodynamic changes in cirrhosis.关键词
体层摄影术,X线计算机/Child-Pugh分级/肝硬化/血流动力学/脾脏Key words
Tomography,X-ray computed/Child-Pugh classification/Cirrhosis/Hemodynamics/Spleen引用本文复制引用
刘璐豪,周舟..双能量CT评估不同Child-Pugh分级肝硬化肝脾血流动力学的初步研究[J].中国中西医结合影像学杂志,2024,22(3):338-341,364,5.基金项目
河南省中医药科学研究专项课题(2018ZY2088). （2018ZY2088）
