国际生殖健康/计划生育杂志2024，Vol.43Issue(3)：249-253,5.DOI:10.12280/gjszjk.20240034
2型糖尿病相关子宫内膜癌与肠道菌群相关性的研究进展
Research Progress on the Correlation between the Endometrial Cancer Associated with Type 2 Diabetes Mellitus and the Intestinal Flora
王芳 1万桃 1杨永秀2
作者信息
- 1. 730000 兰州大学第一临床医学院
- 2. 兰州大学第一医院妇产科,甘肃省妇科肿瘤临床研究中心
- 折叠
摘要
Abstract
Type 2 diabetes mellitus(T2DM)is related to the higher incidence and the increased invasiveness of endometrial cancer(EC).Hyperglycemia,hyperinsulinemia,insulin resistance and obesity in patients with T2DM have been widely studied as potential pathogenesis of EC,and the imbalance of intestinal flora may be the key factor of T2DM-related EC.This paper summarizes the relationships between T2DM and EC,T2DM and intestinal flora,T2DM-related EC and intestinal flora,including the abnormal expression of microRNA,mitochondrial dysfunction,inflammation and adiponectin level,and the progress of intestinal flora in treating T2DM-related EC,in order to provide a reference for the prevention and treatment of T2DM-related EC from the perspective of intestinal flora.关键词
胃肠道微生物组/糖尿病,2型/子宫内膜肿瘤/治疗Key words
Gastrointestinal microbiome/Diabetes mellitus,type 2/Endometrial neoplasms/Therapy引用本文复制引用
王芳,万桃,杨永秀..2型糖尿病相关子宫内膜癌与肠道菌群相关性的研究进展[J].国际生殖健康/计划生育杂志,2024,43(3):249-253,5.
