某儿童医院头孢曲松药物利用评价标准的建立与应用OACSTPCD
Establishment and Application of Drug Use Evaluation for Ceftriaxone in a Children's Hospital
目的:建立针对儿童的头孢曲松药物利用评价(DUE)标准,为规范儿童抗菌药物使用提供参考.方法:参照药品说明书、权威指南及书籍等制定头孢曲松DUE标准并应用于临床;分析比较我院2021年7-9月和2022年7-9月使用头孢曲松的住院病例,评价DUE标准应用情况.结果:2022年7-9月的病程记录、检验指标、禁忌证、联合用药指征以及剂量和频次的符合标准占比较2021年7-9月明显提高,但检验指标、联合用药指征、剂量和频次、药物相互作用方面,仍低于目标值.结论:建立的头孢曲松儿童DUE标准,可有效用于头孢曲松的使用评价,及时发现问题并提出整改措施,促进临床合理用药.
Objective:To establish the drug use evaluation(DUE)for ceftriaxone in children,so as to provide reference for regulating the use of antibiotics in children.Methods:The DUE standard for ceftriaxone was formulated according to the drug instructions,authoritative guidelines and books,and finally applied in clinic.Inpatients treated with ceftriaxone in our hospital from Jul.to Sept.2021 and from Jul.to Sept.2022 were analyzed and compared to evaluate the application of DUE standard.Results:From Jul.to Sept.2022,the compliance standards of the disease course records,test indicators,contraindications,indications of drug combination,and dose and frequency increased significantly compared with those from Jul.to Sept.2021,yet the test indicators,indications of drug combination,dose and frequency,and drug interactions were still lower than the target value.Conclusion:The established DUE standard for ceftriaxone in children can be effectively used for the evaluation,timely detection of problems and rectification measures,and promotion of rational drug use in clinic.
张晓艳;蔡和平;周宬玥
安徽省儿童医院,合肥 230051
药学
儿童头孢曲松合理用药药物利用评价
childrenceftriaxonerational drug usedrug use evaluation
《儿科药学杂志》 2024 (005)
23-26 / 4
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