海南医学院学报2024，Vol.30Issue(9)：715-720,6.DOI:10.13210/j.cnki.jhmu.20230831.002
牙周炎与炎症性肠病的微生物/免疫关系研究进展
Research progress on the relationship between periodontitis and inflammatory bowel disease
摘要
Abstract
Periodontal disease combined with inflammatory bowel disease(IBD)is a common disease in the department of stomatology.Both of them are affected by the imbalance of microbiota and immune reaction in the process of onset,forming a path-ological mutual promotion,leading to the gradual deterioration of the disease.Recent studies have shown that there is a close rela-tionship between periodontal disease and IBD,including direct and indirect pathways.The direct pathway is the translocation of pro-inflammatory microorganisms from the oral cavity to the intestine,and the stimulation of intestinal immunity.Indirect path-ways include systemic immune activation and may be accompanied by non-specific immune function.This paper reviewes the micro-bial/immune interaction between periodontal disease and IBD in recent years,and summarizes the complex pathogenic relationship between periodontal disease and IBD,providing guidance for the treatment of Periodontal disease with IBD.关键词
牙周炎/炎症性结肠炎/微生物/免疫反应Key words
Periodontitis/Inflammatory bowel disease/Microbe/Immune response分类
医药卫生引用本文复制引用
王慧,李永辉,钟晓雪,陈敏哲,薛逢明,贺小宁..牙周炎与炎症性肠病的微生物/免疫关系研究进展[J].海南医学院学报,2024,30(9):715-720,6.基金项目
This study was supported by National Natural Science Foundation of China(82160826) 国家自然科学基金资助项目(82160826) （82160826）
