精准医学杂志2024，Vol.39Issue(2)：155-158,4.DOI:10.13362/j.jpmed.202402013
子痫前期母亲分娩早产儿甲状腺功能的特点及其影响因素分析
Characteristics of thyroid function and its influencing factors in preterm infants born to mothers with preeclampsia
摘要
Abstract
Objective To investigate the characteristics of thyroid function and its influencing factors in preterm infants born to mothers with preeclampsia.Methods A total of 222 preterm infants,who were admitted to the neonatal intensive care unit of our hospital from January to December 2019,were enrolled,and according to the presence or absence of preeclampsia in the mother,they were divided into experimental group with 120 infants and control group with 102 infants.Basic clinical data were col-lected from the preterm infants and their mothers,as well as the results of thyroid function test using peripheral venous blood of preterm infants at 10-14 d after birth.The Student's t-test,a one-way analysis of variance,and the multiple stepwise regression analysis were used to investigate the influencing factors for thyroid function in preterm infants.Results There was no significant difference in maternal thyroid function between the two groups(P＞0.05).The experimental group had a significantly higher se-rum level of thyroid stimulating hormone(TSH)than the control group(t=-2.76,P＜0.01).The multiple stepwise regression analysis showed that systolic pressure of the mother and birth weight of the preterm infant were the main influencing factors for thyroid function in preterm infants(F=7.370,6.334,P＜0.05).Conclusion Preterm infants born to mothers with preeclampsia have a significantly higher serum level of TSH than those born to mothers with normal blood pressure,and there is no significant association between serum TSH level of preterm infants and maternal thyroid function.关键词
子痫前期/分娩/甲状腺功能试验/影响因素分析/婴儿,早产Key words
Pre-eclampsia/Parturition/Thyroid function tests/Root cause analysis/Infant,premature分类
医药卫生引用本文复制引用
刘子艳,姜红,张璐璐,张沂洁,李婷,刘燕..子痫前期母亲分娩早产儿甲状腺功能的特点及其影响因素分析[J].精准医学杂志,2024,39(2):155-158,4.基金项目
山东省医药卫生科技发展计划项目(2016WS0267) （2016WS0267）
