精准医学杂志2024，Vol.39Issue(2)：163-166,4.DOI:10.13362/j.jpmed.202402015
前庭性偏头痛患者大脑皮质厚度异常研究
Cortical thickness abnormalities in patients with vestibular migraine
摘要
Abstract
Objective To investigate cortical thickness changes in patients with vestibular migraine(VM),and to pro-vide a basis for studying the pathogenesis of VM.Methods From June 2021 to December 2022,we enrolled 27 patients with VM visiting the department of neurology of our hospital and 28 healthy volunteers as control group.All the subjects underwent whole-brain magnetic resonance(MR)scanning.Using surface-based morphometry,the thickness of the cortex was analyzed on MR images and compared between the two groups.In the VM group,Spearman correlation analysis was performed to detect the correlation between cortical thickness changes and VM course,headache attack frequency,dizziness attack frequency,and headache intensity on the Visual Analogue Scale(VAS).Results Compared with the control group,patients with VM had a significant decrease in the cortical thickness of the left inferior parietal lobule(Pvertex＜0.01,Pcluster＜0.05).However,there was no signifi-cant correlation between the cortical thickness of the left inferior parietal lobule and the course of VM,headache attack frequency,dizziness attack frequency,or VAS score(P＞0.05).Conclusion The cortical thickness of the left inferior parietal lobule is al-tered in patients with VM.The left inferior parietal lobule may be involved in the pathophysiological process of VM.关键词
偏头痛/前庭疾病/脑皮质厚度/磁共振成像Key words
Migraine disorders/Vestibular diseases/Brain cortical thickness/Magnetic resonance imaging分类
医药卫生引用本文复制引用
乔超,刘衍希,阎文静,刘学军,王海萍..前庭性偏头痛患者大脑皮质厚度异常研究[J].精准医学杂志,2024,39(2):163-166,4.基金项目
山东省医药卫生科技发展计划面上项目(2021BJ-000009) （2021BJ-000009）
