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免疫细胞在肿瘤骨转移骨微环境调控中的作用研究进展

唐亮 朱丽娟 吕成伟 康辉

精准医学杂志2024,Vol.39Issue(2):182-184,186,4.
精准医学杂志2024,Vol.39Issue(2):182-184,186,4.DOI:10.13362/j.jpmed.202402020

免疫细胞在肿瘤骨转移骨微环境调控中的作用研究进展

Research advances in the role of immune cells in the regulation of bone microenvironment in bone metastasis of tumor

唐亮 1朱丽娟 1吕成伟 1康辉1

作者信息

  • 1. 中国人民解放军联勤保障部队第九八九医院骨科,河南洛阳 471031
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摘要

Abstract

The development and progression of tumor is closely associated with the microenvironment in which the tumor is located.In the process of bone metastasis,the numerous immune cells in bone marrow microenvironment play an important role in the colonization of tumor cells and the formation of metastases,and in particular,they can assist tumor cells with immune es-cape.Therefore,it is especially important to explore effective interventions to suppress the immune escape of tumor.This article reviews the role of macrophages,myeloid-derived suppressor cells,and lymphocytes in bone metastasis,so as to provide a refe-rence for the basic research on tumor immunotherapy and clinical treatment.

关键词

肿瘤转移/骨肿瘤/骨和骨组织/肿瘤微环境/肿瘤逃逸/免疫系统/综述

Key words

Neoplasm metastasis/Bone neoplasms/Bone and bones/Tumor microenvironment/Tumor escape/Im-mune system/Review

分类

医药卫生

引用本文复制引用

唐亮,朱丽娟,吕成伟,康辉..免疫细胞在肿瘤骨转移骨微环境调控中的作用研究进展[J].精准医学杂志,2024,39(2):182-184,186,4.

基金项目

第989医院卫生科技计划(9892023YNKT-02A) (9892023YNKT-02A)

精准医学杂志

2096-529X

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