岭南现代临床外科2024，Vol.24Issue(1)：49-53,5.DOI:10.3969/j.issn.1009-976X.2024.01.007
代谢综合征对非三阴型乳腺癌预后的影响
The effect of metabolic syndrome on prognosis of non-triple negative breast cancer
吴文霞 1张萌1
作者信息
- 1. 中山大学孙逸仙纪念医院全科医学科,广州 510289
- 折叠
摘要
Abstract
Objective To explore the prognostic value of metabolic syndrome(MS)and its compo-nents in outcome of patients with non-Triple Negative Breast Cancer(non-TNBC).Methods The study included the newly diagnosed non-TNBC during Jan 1 2016 and Mar 30 2017.Clinical and pathological data were collected,and the patients were followed up for 3 years.The Kaplan-Meier analysis was used to explore the association between the MS and its components and the overall survival(OS).The prognosis factors were analyzed by the multivariable Cox proportional hazards regression models.Results 194 patients were included with 12 in MS group and 168 in non-MS group.During the follow-up,there were 2 patients died in MS group,which OS rate was 81.8%.While in the non-MS group,2 patients died and the OS rate was 98.8%(P<0.05).After adjusting the menopausal status age,tumor stage and pathological factors,MS was the independently risk factor for poor OS(HR=62.788,95%CI:1.342-2937.323,P<0.05).The patients with two or more items of hypertension,hyperglycemia and dyslipidemia had higher death risk,compared with the patient with only one or none of them(HR=23.397,95%CI:1.918-285.405,P<0.05).Conclusion MS was associated with poor prognosis of non-Triple Negative Breast Cancer.关键词
代谢综合征/非三阴型乳腺癌/预后Key words
metabolic syndrome/non-triple negative breast cancer/prognosis分类
医药卫生引用本文复制引用
吴文霞,张萌..代谢综合征对非三阴型乳腺癌预后的影响[J].岭南现代临床外科,2024,24(1):49-53,5.
