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误诊为肺结核瘤的ANCA相关性血管炎临床分析OACSTPCD

Analysis of ANCA-associated Vasculitis Misdiagnosed as Pulmonary Tuber-culoma

中文摘要英文摘要

目的 探讨抗中性粒细胞胞质抗体(ANCA)相关性血管炎的误诊原因及防范措施.方法 回顾分析1例曾误诊的ANCA相关性血管炎的临床资料.结果 本例因下肢红疹伴溃疡入院.曾行"鼻窦炎"手术,术前筛查发现肺部肿物行"肺部肿物切除术",术后病理示肺结核瘤,抗结核治疗无效.入院后结合患者多系统受累表现及实验室、肾穿刺病理检查等诊断为ANCA相关性血管炎,给予糖皮质激素及调节免疫等治疗,症状缓解.结论 ANCA相关性血管炎临床表现多样且不典型,易误诊.临床中应对疑似病例尽早行相关医技检查.

Objective To explore the causes of misdiagnosis of anti-neutrophil cytoplasmic antibodies(ANCA)-associatedvasculitis and the preventive measures.Methods The clinical data of 1 patient with ANCA-associated vasculitis misdiagnosed were retrospectively analyzed.Results The patient was admitted to the hospital due to red rash of lower extrem-ity with ulcer.Operation for sinusitis had been performed in other hospitals,and pulmonary mass resection was performed in another hospital because pulmonary mass had been found during preoperative screening.Postoperative pathology revealed pul-monary tuberculoma,and the treatment was ineffective after anti-tuberculosis therapy.After admission,the patient was diag-nosed with ANCA-associated vasculitis based on the manifestations of multi-system involvement,laboratory examination and pathological examination of renal puncture.The symptoms were relieved by glucocorticoid and modulated immunotherapy.Conclusion The clinical manifestations of ANCA-associated vasculitis are diverse and atypical,which,therefore,is more likely to lead to misdiagnosis.In clinical practice,relevant medical examination should be performed as soon as possible in suspected cases.

胡以恒;伊力努尔·哈力甫;康晓静;沈晓峰

830001 乌鲁木齐,新疆维吾尔自治区人民医院皮肤性病科新疆皮肤病临床医学研究中心新疆皮肤病研究重点实验室830011 乌鲁木齐,新疆医科大学第五附属医院皮肤科

临床医学

抗中性粒细胞胞质抗体相关性血管炎误诊肺结核瘤抗结核药抗体,抗核抗体,抗中性白细胞胞质抗蛋白酶3抗体糖皮质激素类

Anti-neutrophil cytoplasmic antibody-associated vasculitisMisdiagnosisPulmonary tuberculomaAnti-tubercular agentsAntibodies,antinuclearAntibodies,antineutrophil cytoplasmicAnti-protease 3 antibodyGlucocorticoids

《临床误诊误治》 2024 (004)

16-19 / 4

新疆维吾尔自治区"天山英才"培养计划(2022TSYCLJ0025)

10.3969/j.issn.1002-3429.2024.04.004

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