上海针灸杂志2024，Vol.43Issue(5)：510-515,6.DOI:10.13460/j.issn.1005-0957.2024.05.0510
脐灸配合健脾益气通便汤治疗儿童功能性便秘的疗效观察
Therapeutic observation of umbilical moxibustion plus Jian Pi Yi Qi Tong Bian Tang for functional constipation in children
摘要
Abstract
Objective To observe the clinical efficacy of umbilical moxibustion plus Jian Pi Yi Qi Tong Bian Tang in treating functional constipation in children and the effects on the symptom score of traditional Chinese medicine(TCM),intestinal microbiota,and serum intestinal neurotransmitters.Method A total of 106 children with functional constipation were randomized into a treatment group with 56 cases and a control group with 50 cases.The treatment group received umbilical moxibustion plus Jian Pi Yi Qi Tong Bian Tang,and the control group only received oral administration of Jian Pi Yi Qi Tong Bian Tang for treatment.The two groups were observed for changes in each primary symptom score,TCM symptom score,intestinal microbiota(counts of Bifidobacterium,Lactobacillus,and Escherichia coli),and the levels of serum intestinal neurotransmitters[nitric oxide(NO),substance P(SP),and somatostatin(SS)]after the treatment.The clinical efficacy and adverse reaction rate were compared between the two groups.Result After the treatment,each primary symptom score,TCM symptom score,and serum levels of NO and SS dropped in both groups,and the counts of Bifidobacterium,Lactobacillus,and Escherichia coli and the serum SP level increased,all showing statistical significance(P＜0.05).After the intervention,each primary symptom score,TCM symptom score,and serum levels of NO and SS were lower in the treatment group than in the control group,and the counts of Bifidobacterium,Lactobacillus,and Escherichia coli and the serum SP level were higher in the treatment group;the between-group differences were statistically significant(P＜0.05).The total effective rate after the treatment and the adverse reaction rate during the trial were 96.4%and 5.4%,respectively,in the treatment group,versus 84.0%and 8.0%in the control group;the two groups had a significant difference in comparing the total effective rate(P＜0.05).Conclusion Umbilical moxibustion plus Jian Pi Yi Qi Tong Bian Tang is effective in treating children's functional constipation.This method can improve clinical symptoms and TCM symptoms,correct disordered intestinal dysbiosis,regulate bowel flora,and restore intestinal neurotransmitter levels.关键词
灸法/脐灸/药饼灸疗法/便秘,功能性/儿童/肠道微生态/肠神经递质/健脾益气通便汤Key words
Moxibustion/Umbilical moxibustion/Medicinal cake-partitioned moxibustion/Constipation,Functional/Children/Intestinal microbiota/Intestinal neurotransmitters/Jian Pi Yi Qi Tong Bian Tang分类
中医学引用本文复制引用
陈欢,赵敏,耿文婧..脐灸配合健脾益气通便汤治疗儿童功能性便秘的疗效观察[J].上海针灸杂志,2024,43(5):510-515,6.基金项目
河北省全科医学临床科研基金(2020QK029) （2020QK029）
