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针刺配合穴位贴敷治疗失眠的疗效观察OACSTPCD

Therapeutic observation of acupuncture combined with point application for insomnia

中文摘要英文摘要

目的 观察针刺配合芳香型穴位贴敷治疗失眠的临床疗效.方法 将90 例失眠患者随机分为治疗组和对照组,每组 45例.治疗组采用针刺配合芳香型穴位贴敷(吴茱萸、肉桂、苏合香)治疗,对照组采用针刺配合常规穴位贴敷(吴茱萸、肉桂)治疗.观察两组治疗前及治疗 2、4 周后匹兹堡睡眠质量指数(Pittsburgh sleep quality index,PSQI)各项评分(睡眠质量、入睡时间、睡眠时间、睡眠效率、睡眠障碍、日间功能障碍、总分)及多导睡眠监测(polysomnography,PSG)各项指标[总睡眠时间及非快速眼动(non-rapid eye movement,NREM)-Ⅰ期、NREM-Ⅱ期、NREM-Ⅲ期、快速动眼(rapid eye movement,REM)期时间]的变化情况,并比较两组临床疗效.结果 治疗组治疗2、4 周后除睡眠时间外,其余各项PSQI各项评分均较同组治疗前显著下降(P<0.05);对照组治疗2、4周后除睡眠效率外,其余各项PSQI各项评分均较同组治疗前显著下降(P<0.05).治疗组治疗2、4 周后睡眠质量评分、睡眠障碍评分及总分明显低于对照组,差异均具有统计学意义(P<0.05).治疗组治疗 2 周后NREM-Ⅰ期、NREM-Ⅱ期时间均较同组治疗前显著减少,NREM-Ⅲ期时间显著增加,差异均具有统计学意义(P<0.05);治疗4周后NREM-Ⅰ期、NREM-Ⅱ期及REM期时间均较同组治疗前显著减少,总睡眠时间及NREM-Ⅲ期时间均显著增加,差异均具有统计学意义(P<0.05).对照组治疗4周后NREM-Ⅰ期、NREM-Ⅱ期时间均较同组治疗前显著减少,总睡眠时间及NREM-Ⅲ期时间均显著增加,差异均具有统计学意义(P<0.05).两组治疗 2 周后NREM-Ⅰ期、NREM-Ⅱ期、NREM-Ⅲ期时间及治疗 4 周后总睡眠时间及NREM-Ⅲ期、REM期时间比较,差异均具有统计学意义(P<0.05).治疗组总有效率为 77.8%,明显高于对照组的 66.7%,两组比较差异具有统计学意义(P<0.05).结论 针刺配合芳香型穴位贴敷是一种治疗失眠的有效方法,其起效时间较针刺配合常规穴位贴敷更短.

Objective To observe the clinical efficacy of acupuncture plus aromatic point application in treating insomnia.Method Ninety patients with insomnia were randomized into a treatment group and a control group,with 45 cases in each group.The treatment group was intervened by acupuncture plus aromatic point application[Wu Zhu Yu(Fructus Evodiae),Rou Gui(Cortex Cinnamomi),and Su He Xiang(Styrax)],and the control group was treated with acupuncture plus conventional point application[Wu Zhu Yu(Fructus Evodiae)and Rou Gui(Cortex Cinnamomi)].Before and after 2 and 4 weeks of treatment,the following outcome measures were observed:the Pittsburgh sleep quality index(PSQI)scores(sleep quality,sleep latency,sleep duration,sleep efficiency,sleep disturbance,diurnal dysfunction,and general score)and polysomnography parameters[total sleep time and the lengths of non-rapid eye movement(NREM)stage Ⅰ,NREM stage Ⅱ,NREM stage Ⅲ,and rapid eye movement(REM)stage].The clinical efficacy was also compared between the two groups.Result After 2 and 4 weeks of treatment,the scores for all components of the PSQI,except for sleep duration,significantly decreased compared to the same group's pre-treatment scores(P<0.05);After 2 and 4 weeks of treatment,the scores for all components of the PSQI,except for sleep efficiency,significantly decreased in the control group compared to their pre-treatment scores(P<0.05);the sleep quality,sleep disturbance,and general scores were lower in the treatment group than in the control group with statistical significance(P<0.05).After 2-week treatment,the treatment group showed a significant decrease in the lengths of NREM stages Ⅰ and Ⅱ and a significant increase in the length of NREM stage Ⅲ compared to the baseline(P<0.05);after 4-week treatment,the treatment group showed a significant decrease in the lengths of NREM stages Ⅰ and Ⅱ and REM stage and a significant increase in the total sleep time and the length of NREM stage Ⅲ compared to the baseline(P<0.05).After 4-week treatment,the control group had a significant decrease in the lengths of NREM stages Ⅰ and Ⅱand a significant increase in the total sleep time and the length of NREM stage Ⅲ compared to the baseline(P<0.05).The two groups were significantly different in comparing the lengths of NREM stages Ⅰ,Ⅱ,and Ⅲ after 2-week treatment and in comparing the total sleep time and the lengths of NREM stage Ⅲ and REM stage after 4-week treatment(P<0.05).The total effective rate was 77.8%in the treatment group,higher than 66.7%in the control group,and the difference was statistically significant(P<0.05).Conclusion Acupuncture plus aromatic point application is an effective method in treating insomnia,and it takes a shorter time to act compared to the conventional point application.

顾启超;高垣;沈卫东

上海中医药大学,上海 201203上海中医药大学附属曙光医院,上海 201203

中医学

针刺疗法穴位贴敷法失眠睡眠障碍芳香疗法匹兹堡睡眠质量指数多导睡眠监测

Acupuncture therapyPoint application therapyInsomniaSleep disordersAromatherapyPittsburgh sleep quality indexPolysomnography

《上海针灸杂志》 2024 (005)

527-533 / 7

上海市浦东新区卫生系统名中医工作室建设项目(PWRzm2020-05);上海市中西医结合学会科研基金项目(SHCIM202102)

10.13460/j.issn.1005-0957.2024.05.0527

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