日用化学品科学2024，Vol.47Issue(5)：14-20,7.DOI:10.3969/j.issn.1006-7264.2024.05.004
糖脂对痘痘肌的护理功效研究
Research on the skincare effect of glycolipids on acne-prone skin
王会玉 1查建生 1童莉 1晏晓东 2王靖2
作者信息
- 1. 南京斯拜科生物科技股份有限公司,江苏 南京 211800
- 2. 江南大学 化学与材料工程学院 江苏 无锡 214122
- 折叠
摘要
Abstract
Glycolipids are lipid compounds,which are a type of amphiphilic molecules containing glycosyl ligands.This experiment studied the efficacy of glycolipids in acne-prone skin care from the aspects of antibacterial,anti-inflammatory,anti-allergic,oil control,soothing and repairing.The research results show that glycolipids have excellent antibacterial properties against P.acnes.When the dosage of glycolipids reaches 10 μg/mL,the inhibition rate of glycolipids on lipid synthesis in SZ95 cells can reach 20%.Glycolipids can have an inhibitory effect on the release of inflammatory factors IL-6 and NO induced by LPS in RAW264.7 cells.When the glycolipid concentration is 15 mg/mL,the inhibition rate of glycolipid on hyaluronidase reaches 45.8%.When the glycolipid concentration is 25 μg/mL,the inhibition rate on calcium ion concentration reaches 45.3%.Glycolipids have a significant promoting effect on wound healing.Furthermore,human efficacy evaluation shows that glycolipid products have comprehensive skincare effects on acne-prone skin.This study will help further promote the application of glycolipids in cosmetic products,especially in skin care products for acne-prone skin.关键词
糖脂/痘痘肌/控油/抑菌/抗炎Key words
glycolipid/acne skin/oil control/antibacterial/anti-inflammatory分类
化学化工引用本文复制引用
王会玉,查建生,童莉,晏晓东,王靖..糖脂对痘痘肌的护理功效研究[J].日用化学品科学,2024,47(5):14-20,7.
