摘要
Abstract
Compared to adult skin,the skin of infants and children is thinner,less sebum,and more sensitive to external stimuli,therefore requiring more gentle cleansing products.This study screened suitable surface active compositions through Zein test,red blood cell test,Hen's egg test-chorioallantoic membrane,3D skin model,and sunscreen cleaning test.When the ratio of sodium cocoylglutamate/cocoamide propyl betaine(w/w)is between 3∶1 and 1∶3,the mildness and cleaning power of the composition are relatively ideal,and the addition of sophorolipids can further improve the gentleness of the surface active composition.A HaCaT cell damage model was established through UVB induction to explore the role of sophorolipids.The results show that sophorolipids have the effect of improving skin barrier function,which is beneficial for skin moisturizing and repairing.Finally,the extraction of dissolution factors by the vibration cup method was used to study the stimulation of the surface active composition on the stratum corneum.The results show that the composition has less dissolution of natural moisturizing factors and lipids in the skin,and has less impact on the skin compared to octyl/decyl glucosides,making it more suitable for infant and child skin.关键词
表面活性剂/槐糖脂/温和性/儿童Key words
surfactants/sophorolipids/mildness/children分类
化学化工
