中草药添加剂对断奶湖羊生长性能、血清抗氧化指标及免疫功能的影响OA北大核心CSTPCD

The aim of this experiment was to study the effects of different doses of Chinese herbal additives on the growth performance,serum antioxidant indexes,and immune function of Hu sheep.A total of 48 two-month-old weaned lambs in good health and similar weight were selected and randomly divided into four groups,with four replicates in each group.The control group was fed a basal diet,and the experimental group Ⅰ,group Ⅱ,and group m were fed the diets supplemented with 0.010,0.025,0.050 g/kg of Chinese herbal additives,respectively.The pre-trial period was seven days and the formal period was 90 days.The results showed that the average daily weight gain of the experimental group Ⅱincreased by 22.22％compared with that of the control group from 61 to 90 days(P＜0.05),and the feed to gain ratio decreased by 18.85％(P＜0.01).At 30 d,compared with the control group,the concentrations of total protein(TP)and interferon-γ(IFN-γ)in the experimental group Ⅱ increased significantly(P＜0.05).Compared with the experimental group Ⅲ,the concentrations of immunoglobulin G(IgG),interleukin 4(IL-4),interleukin 6(IL-6),tumor necrosis factor-α(TNF-α),and IFN-γ in experimental group Ⅱsignificantly or extremely increased(P＜0.05 or P＜0.01).At 60 d,the concentration of the reduced glutathione(GSH)in the exprimental group Ⅱextremely increased compared with the control group and the experimental group m(P＜0.01).Compared with the control group and the experimental group m,immunoglobulin A(IgA),IgG,IL-4,and IFN-γincreased extremely(P＜0.01).The concentration of IL-6 in the exprimental group Ⅱ were significantly higher the experimental group Ⅲ(P＜0.05),and the concentrations of IgA and IL-4 were significantly or extremely higher than those of the experimental group Ⅰ(P＜0.05 or P＜0.01).At 90 d,the concentration of IgA in the experimental group Ⅱ was extremely higher than that of the control group(P＜0.01),and the concentrations of immunoglobulin M(IgM)and IFN-γwere significantly higher than that of the experimental group Ⅲ(P＜0.05).The study indicates that the Chinese herbal medicine additive can promote the growth of Hu sheep,enhance the antioxidant ability and immunity of the animal body,and the appropriate amount of Chinese herbal medicine additive is 0.025 g/kg.