生殖医学杂志2024，Vol.33Issue(5)：687-694,8.DOI:10.3969/j.issn.1004-3845.2024.05.021
评估胚胎发育潜能研究的新进展
Progress in the study of evaluating embryonic development potential
摘要
Abstract
Embryonic development potential will be related to the selection of single embryo transfer in assisted reproduction outcome and the final clinical pregnancy result.Because of its advantages of simplicity,convenience,low-priced,high stability and great efficiency,the morphological evaluation has become the most widely used method to evaluate embryonic development potential in assisted reproductive laboratory.The birth and rise of time-lapse(TL)technology provides a means for assisted reproductive laboratory to record the dynamic complete process of embryonic development in real time.Metabolomics study provides an accurate physiologically assessment of embryonic development potential by detecting metabolites such as glucose,amino acids,NAD(P)H and FAD+.The application of preimplantation genetic testing(PGT)tests embryos for severe genetic diseases or chromosomal abnormalities(aneuploidy).This article reviews the progress of the above four methods for evaluating embryonic development potential.关键词
胚胎发育潜能/时差成像技术/植入前遗传学检测/形态学评估Key words
Embryonic development potential/Time-lapse technology/Preimplantation genetic testing/Morphological evaluation分类
医药卫生引用本文复制引用
黄梓楷,张智博,陶萍,李友筑..评估胚胎发育潜能研究的新进展[J].生殖医学杂志,2024,33(5):687-694,8.基金项目
福建省科技厅自然科学基金项目(2022J011378) （2022J011378）
