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液基薄层细胞检测联合高危型人乳头瘤病毒检测在宫颈癌前病变诊断中的价值

叶艳 单灵钰

妇儿健康导刊2024,Vol.3Issue(9):104-107,4.
妇儿健康导刊2024,Vol.3Issue(9):104-107,4.

液基薄层细胞检测联合高危型人乳头瘤病毒检测在宫颈癌前病变诊断中的价值

Value of thin-prep cytology test combined with high-risk human papilloma virus detection in the diagnosis of cervical precancerous lesions

叶艳 1单灵钰2

作者信息

  • 1. 兰州市妇幼保健院妇三科,甘肃兰州 730000
  • 2. 兰州市妇幼保健院内镜中心,甘肃兰州 730000
  • 折叠

摘要

Abstract

Objective To analyze the value of thin-prep cytology test(TCT)combined with high-risk human papilloma virus(HPV)detection in the diagnosis of cervical precancerous lesions.Methods A total of 487 patients with suspected cervical precancerous lesions admitted to Lanzhou Maternal and Child Health Hospital from January to June 2023 were selected as the study objects.All of them received TCT and high-risk HPV examination,and pathological examination was used as the gold standard to analyze the diagnostic efficacy of different detection methods.Results Among the 487 patients,131 cases of precancerous lesions were detected by pathological examination.Using the results of pathological examination as the gold standard,the sensitivity,accuracy and negative predictive value of TCT combined with high-risk HPV detection were higher than those of single examination(P<0.05).Kappa test showed that the results of TCT combined with high-risk HPV detection had excellent consistency with the results of pathological examination(Kappa=0.969,P=0.000).Conclusion TCT combined with high-risk HPV detection in the diagnosis of cervical precancerous lesions has high sensitivity and accuracy,and is worthy of clinical application.

关键词

宫颈癌前病变/液基薄层细胞检测/高危型人乳头瘤病毒/诊断效能

Key words

Cervical precancerous lesion/Thin-prep cytology test/High-risk human papilloma virus/Diagnostic efficacy

分类

医药卫生

引用本文复制引用

叶艳,单灵钰..液基薄层细胞检测联合高危型人乳头瘤病毒检测在宫颈癌前病变诊断中的价值[J].妇儿健康导刊,2024,3(9):104-107,4.

基金项目

兰州市科技计划项目(2022-5-160). (2022-5-160)

妇儿健康导刊

2097-115X

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