摘要
Abstract
Objective To analyze the effects of Yunpi Zhixie Decoction combined with Yuping SAN treatment on immune function and gastrointestinal microecology of children with prolonged diarrhea.Methods The clinical data of 113children with per-sistent diarrhea treated in our hospital from July 2020to August 2022were selected,and they were divided into control group of 55cases(Western medicine treatment+Yunpi Xueliang decoction)and observation group of 58cases(Western medicine treat-ment+Yunpi Xueliang decoction+Yuping SAN)according to different treatment regiments.The total curative effect rate,TCM syndrome score,immune function,gastrointestinal microecology,adverse reaction and recurrence rate were compared between the two groups.Results After treatment,the total curative effect rate of the observation group was higher than that of the control group,and the TCM syndrome score of the observation group was lower than that of the control group(P＜0.05).After treat-ment,the increase of CD4+,CD4+/CD8+,IgA and IgG levels in observation group was bigger than that in control group(P＜0.05).After treatment,the number of Escherichia coli and enterococcus in observation group was lower than that in control group,while the number of bifidobacterium,lactobacillus and bacterioid bacteria in observation group was higher than that in con-trol group(P＜0.05).No adverse reactions such as vomiting,nausea and dehydration were observed in the two groups.After 6months of follow-up,the recurrence rate of observation group was lower than that of control group(x2=7.918,P＜0.05).Con-clusion Yunpi Zhixie Decoction combined with Yuping SAN can improve the total curative effect rate of children with prolonged di-arrhea,reduce clinical symptoms,improve immune function and regulate gastrointestinal microecology.关键词
运脾止泻汤/玉屏散/迁延性腹泻/免疫功能/胃肠道微生态Key words
Yunpi Zhixie Decoction/Jade screen powder/Persistent diarrhea/Immune function/Gastrointestinal micro-ecology分类
医药卫生
