医学信息2024，Vol.37Issue(9)：168-172,5.DOI:10.3969/j.issn.1006-1959.2024.09.035
肠道特征性微生物菌群在结直肠癌诊治中的研究现状
Research Status of Intestinal Characteristic Microbial Flora in the Diagnosis and Treatment of Colorectal Cancer
摘要
Abstract
Colorectal cancer(CRC)is one of the malignant tumors with high morbidity and mortality in the world.It is urgent to find characteristic diagnostic markers and carry out early intervention and treatment.Previous studies have shown that intestinal microflora is closely related to the occurrence and development of CRC.Through the sequencing analysis of the metagenome or 16S rRNA of intestinal microflora,CRC-related intestinal characteristic microflora is identified,and its abundance and composition changes are expected to be used as potential CRC diagnostic markers.This article reviews the characteristics of intestinal flora changes in colorectal cancer,detection methods and their role as biomarkers in the diagnosis,progression,staging,treatment and prognosis of CRC,in order to provide new ideas for the clinical diagnosis and treatment of CRC.关键词
肠道菌群/结直肠癌/生物标志物Key words
Intestinal flora/Colorectal cancer/Biomarkers分类
医药卫生引用本文复制引用
陈竹芳,杜冀晖..肠道特征性微生物菌群在结直肠癌诊治中的研究现状[J].医学信息,2024,37(9):168-172,5.基金项目
2022年深圳市南山区科技计划重点项目(编号:NS2022001) （编号:NS2022001）
