医学信息2024，Vol.37Issue(9)：173-178,183,7.DOI:10.3969/j.issn.1006-1959.2024.09.036
铁死亡在年龄相关性黄斑变性中的研究近况
Recent Research on Ferroptosis in Age-related Macular Degeneration
刘宇轩 1夏清艳2
作者信息
- 1. 长春中医药大学中医学院,吉林长春 130000
- 2. 长春中医药大学附属医院眼科,吉林长春 130021
- 折叠
摘要
Abstract
With the popularity of electronic products and the improvement of people's living standards in recent years,age-related macular degeneration(AMD)has become one of the three major blinding eye diseases in China.The incidence of AMD is increasing year by year,which seriously affects people's vision and quality of life.Although studies have shown that its occurrence may be related to factors such as genetics,oxidative stress,choroidal vascular dysfunction,and inflammatory response,the specific pathogenesis is still unclear.Ferroptosis is a newly discovered way of cell death in recent years.Studies at home and abroad have reported its possible correlation with the occurrence and development of AMD.Intervention of ferroptosis pathway has become a potential strategy for the treatment of AMD.This article reviews the role of retinal iron metabolism and ferroptosis in the pathogenesis of AMD in recent years,as well as the currently known treatment methods,in order to provide a new focus for the treatment of AMD.关键词
年龄相关性黄斑变性/铁死亡/致盲性眼病Key words
Age-related macular degeneration/Ferroptosis/Blinding eye disease分类
医药卫生引用本文复制引用
刘宇轩,夏清艳..铁死亡在年龄相关性黄斑变性中的研究近况[J].医学信息,2024,37(9):173-178,183,7.
