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5-HTR1A基因rs6295多态性与抑郁症伴自伤行为的相关研究

郁德波 林志雄 林举达

医学信息2024,Vol.37Issue(9):179-183,5.
医学信息2024,Vol.37Issue(9):179-183,5.DOI:10.3969/j.issn.1006-1959.2024.09.037

5-HTR1A基因rs6295多态性与抑郁症伴自伤行为的相关研究

Related Research on rs6295 Polymorphism of 5-HTR1A Gene and Depression with Self-injury Behavior

郁德波 1林志雄 2林举达2

作者信息

  • 1. 广东医科大学第一临床医学院,广东 湛江 524001
  • 2. 广东医科大学附属医院精神心理科,广东 湛江 524001
  • 折叠

摘要

Abstract

Depression is a chronic disease with high incidence.However,the etiology and pathogenesis of depression are still poorly understood.Its strong genetic ability and genetic basis have been well confirmed by family,twin and adoption studies,suggesting that rs6295 polymorphism of 5-HTR1A promoter is associated with depression with self-injury behavior.This article reviews the pathogenesis,research status and treatment progress of rs6295 polymorphism of 5-HTR1A gene and depression with self-injury behavior,in order to provide a reference for predicting the genetic susceptibility of depression with NSSI.

关键词

人5-羟色胺受体1A/抑郁症/自伤行为/基因多态性

Key words

Human serotonin receptor 1A/Depression/Self-injury behavior/Gene polymorphism

分类

医药卫生

引用本文复制引用

郁德波,林志雄,林举达..5-HTR1A基因rs6295多态性与抑郁症伴自伤行为的相关研究[J].医学信息,2024,37(9):179-183,5.

医学信息

1006-1959

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