针刺研究2024，Vol.49Issue(5)：534-543,10.DOI:10.13702/j.1000-0607.20230099
揿针治疗变应性鼻炎临床疗效的Meta分析
Meta-analysis on clinical efficacy of ringheaded thumbtack needle in the treatment of allergic rhinitis
摘要
Abstract
Objective To evaluate the efficacy and safety of ringheaded thrumbtack needle in the treatment of allergic rhinitis(AR).Methods Clinical studies about treatment of AR with ringheaded thrumbtack needle were searched from databases of CNKI,Wanfang,China Science and Technology Journal,China Biology Medicine disc,PubMed,Embase and Web of Science from their inception to November 2022.Two researchers independently screened the literature and collected related information.The total effective rate,visual analogue scale(VAS)for AR,rhinoconjunctivitis quality of life questionnaire(RQLQ),and recurrence rate were the main outcome indicators.Secondary outcome indicators included quantitative scores of symptoms and signs,'quartering'symptom evaluation scale,etc.All the included studies were subjected to Meta-analysis using Stata software.Results A total of 22 clinical studies involving 1491 participants were included.The results of Meta-analysis indicated that the total effective rate of ringheaded thrumbtack needle in the treatment of AR was higher than that of traditional Chinese and Western medicine[RR=1.20,95%CI(1.14,1.26),P<0.001],and recurrence rate is lower than conventional therapy[OR=0.35,95%CI(0.14,0.89),P=0.027].Moreover,The VAS score[WMD=-1.30,95%CI(-1.85,-0.75),P<0.001]and RQLQ score[WMD=-6.75,95%CI(-12.74,-0.76),P=0.027]of AR treated by ringheaded thrumbtack needle were lower than those of traditional Chinese and Western medicine.Conclusion Ringheaded thrumbtack needle can improve the total effective rate,reduce the disease recurrence,and improve the symptoms of discomfort when AR outbreaks,and has no significant adverse reactions.However,the reliability is limited.Thus,it is still necessary to improve the level of evidence quality by including researches with large samples,rigorous design and international standards.关键词
变应性鼻炎/揿针/临床研究/临床疗效/安全性/Meta分析Key words
Allergic rhinitis/Ringheaded thrumbtack needle/Clinical studies/Clinical efficacy/Safety/Meta-analysis引用本文复制引用
何水恩,凌曦淘,刘一铭,陈汉华..揿针治疗变应性鼻炎临床疗效的Meta分析[J].针刺研究,2024,49(5):534-543,10.基金项目
国家中医药管理局罗笑容全国名老中医药专家传承工作室建设项目(No.14GG2X02) （No.14GG2X02）
