中国医疗设备2024，Vol.39Issue(5)：133-136,154,5.DOI:10.3969/j.issn.1674-1633.2024.05.022
基于压缩感知EPI的ASL技术在健康志愿者脑灌注成像中的应用研究
Application Study of ASL Technology Based on EPI Combined with Compressed Sensing in Cerebral Perfusion Imaging of Healthy Volunteers
摘要
Abstract
Objective To investigate the application value of arterial spin labeling(ASL)technology based on echo planer imaging(EPI)combined with compressed sensing(CS)(EPICS-ASL)in the cerebral perfusion imaging,and compare with conventional EPI-ASL sequence.Methods A total of 30 volunteers were collected prospectively to underwent EPICS-ASL and conventional EPI-ASL sequences scanning.Basal ganglia,gray matter,white matter,brainstem and cerebellum were selected as region of interest(ROI)on the original ASL images.The signal to noise ratio(SNR)of each ROI and contrast to noise ratio of gray matter/white matter(CNRgray/white matter)were measured and calculated.The image quality of the two groups was scored qualitatively by two independent double-blind physicians using the 4-point method.The paired t-test was used to compare the SNR and CNRgray/white matter of ROIs of the two groups of images,and the rank sum test was used to compare the image quality between the two groups.Results Objective evaluation showed that the SNR and CNRgray/white matter of EPICS-ASL group were batter than those of conventional EPI-ASL group(all P<0.001).Subjective evaluation showed that the image quality scores of EPICS-ASL group were also better than those of conventional EPI-ASL group(all P<0.001).Conclusion Compared with conventional EPI-ASL sequence,the image SNR and CNR of EPICS-ASL sequence is better,and the image quality of EPICS-ASL sequence is higher,which has the potential of further clinical application.关键词
动脉自旋标记/压缩感知/平面回波序列/敏感度编码技术Key words
arterial spin labeling/compressed sensing/echo planar imaging/sensitivity encoding technology分类
医药卫生引用本文复制引用
卞红丽,王建伟,王敏,刘俊..基于压缩感知EPI的ASL技术在健康志愿者脑灌注成像中的应用研究[J].中国医疗设备,2024,39(5):133-136,154,5.基金项目
国家自然科学基金(81671258). （81671258）
