miR-146、miR-26水平与支气管哮喘患者气道炎症及气道重塑的关系OA
Relationship Between miR-146,miR-26 Levels and Airway Inflammation,Airway Remodeling in Patients with Bronchial Asthma
目的 探讨miR-146、miR-26在支气管哮喘患者气道炎症及气道重塑中的作用及机制.方法 收集2021年3月-2023年1月在重庆市南岸区人民医院就诊的75例支气管哮喘患者(哮喘组)和25名健康体检者(对照组),检测血液和呼吸中的相关分子,用HRCT扫描测量气道的形状和大小.分析miR-146、miR-26水平与哮喘严重程度、气道炎症及气道重塑的相关性.结果 哮喘组miR-146、miR-26水平低于对照组,且随着哮喘严重程度的增加而降低(P…查看全部>>
Objective To investigate the role and mechanism of miR-146,miR-26 in airway inflammation and airway remodeling in patients with bronchial asthma.Methods A total of 75 patients with bronchial asthma(asthma group)and 25 healthy subjects(control group)were collected from March 2021 to January 2023 in Chongqing Nan'an District People's Hospital.The related molecules in blood and respiration were detected,and the shape and size of the airway were measured by HRCT…查看全部>>
董扬;傅应亚;方伟
重庆市南岸区人民医院呼吸内科,重庆 400000重庆市第七人民医院呼吸内科,重庆 400000重庆市南岸区人民医院呼吸内科,重庆 400000
临床医学
支气管哮喘微小RNA呼出气一氧化氮嗜酸性粒细胞气道重塑
Bronchial asthmaMicroRNAExhaled nitric oxideEosinophilsAirway remodeling
《医学信息》 2024 (9)
130-133,4
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