中国兽医科学2024，Vol.54Issue(4)：541-545,5.DOI:10.16656/j.issn.1673-4696.2024.0077
分泌型免疫球蛋白A和肠道菌群相互作用的研究进展
Advance on the interaction between sIgA and gut microbiota
摘要
Abstract
Secretory immunoglobulin A(sIgA)is the most abundant antibody type in intestinal mu-cosal tissues.sIgA,together with mucus and antimicrobial peptides,forms the first line of host de-fense of intestinal epithelial cells,to protect against intestinal pathogens.sIgA can not only pre-vent the invasion of pathogenic microorganisms and neutralize toxins,but also regulate the composi-tion of intestinal microbiota,to maintain the gut homeostasis.Our review delineates the synthesis and secretion pathways of sIgA in the intestines,and systematic discussion about the interactions between gut microbiota and sIgA.关键词
分泌型免疫球蛋白A/肠道菌群/相互作用Key words
secretory immunoglobulin A/gut microbiota/interactions between the gut microbiota and sIgA分类
农业科技引用本文复制引用
时志琪,王玉桂,李晓璐,王帅,郭爱疆..分泌型免疫球蛋白A和肠道菌群相互作用的研究进展[J].中国兽医科学,2024,54(4):541-545,5.基金项目
国家自然科学基金项目(32172878) （32172878）
甘肃省杰出青年基金项目(21JR7RA027) （21JR7RA027）
