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食管癌外科术后消化道瘘发生的危险因素分析

陈桃 杨佳 武振宇 张耀 陈磊

局解手术学杂志2024,Vol.33Issue(5):420-424,5.
局解手术学杂志2024,Vol.33Issue(5):420-424,5.DOI:10.11659/jjssx.12E023080

食管癌外科术后消化道瘘发生的危险因素分析

Analysis of risk factors for gastrointestinal fistula after esophageal cancer surgery

陈桃 1杨佳 1武振宇 1张耀 2陈磊1

作者信息

  • 1. 陆军军医大学第一附属医院消化内科,重庆 400038
  • 2. 陆军军医大学流行病学教研室,重庆 400038
  • 折叠

摘要

Abstract

Objective To investigate the risk factors for gastrointestinal fistula after esophageal cancer surgery.Methods The clinical data of 437 patients who underwent esophagectomy in our hospital were retrospectively analyzed.According to whether gastrointestinal fistula occurred after operation,they were divided into the study group(n=157)and the control group(n=280).The related risk factors of the ocurrence of postoperative gastrointestinal fistula were screened by univariate and multivariate analyses.Results The results of the univariate analysis showed that there were statistically significant differences of patients between the two groups in terms of operation time,anastomotic site,tumor location,tumor infiltration depth,surgical method,pleural adhesion,reinforcement suture of anastomotic stoma,post-operative pulmonary infection,and postoperative incision infection(P<0.05).Multivariate Logistic regression analysis showed that pleural adhesion,operation time≥4.5 hours,postoperative pulmonary infection,and postoperative incision infection were independent risk factors for the occurence of postoperative gastrointestinal fistula(P<0.05).The reinforcement suture of anastomotic stoma and the increase of the first postoperative hemoglobin level were independent protective factors for the occurrence of postoperative gastrointestinal fistula(P<0.05).Conclusion Controlling operation time,applying active anti-infection measures,implementing dressing changes,taking reinforcement suture of anastomotic stoma,and correcting of anemia may help to reduce the occurrence of gastrointestinal fistulas after esophagectomy.

关键词

食管癌/外科手术/消化道瘘/危险因素

Key words

esophageal cancer/surgical operation/gastrointestinal fistula/risk factors

分类

医药卫生

引用本文复制引用

陈桃,杨佳,武振宇,张耀,陈磊..食管癌外科术后消化道瘘发生的危险因素分析[J].局解手术学杂志,2024,33(5):420-424,5.

基金项目

重庆市卫生适宜技术推广项目(2018JSTG022) (2018JSTG022)

局解手术学杂志

OACSTPCD

1672-5042

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