中国畜牧兽医2024，Vol.51Issue(5)：1979-1987,9.DOI:10.16431/j.cnki.1671-7236.2024.05.019
单细胞测序及其在动物繁殖机理研究中的作用
The Role of Single-cell Sequencing in Animal Reproductive Mechanism Research
摘要
Abstract
Single-cell sequencing is a high-throughput sequencing technique based on obtaining all genetic information at the level of a single cell.It reveals the intracellular dynamics of individual cells and answer biological questions with high-dimensional catalogs of millions of cells,including genomics,transcriptomics,chromatin accessibility,epigenomics,and proteomics data across species.Within the domain of animal reproduction,single-cell sequencing has emerged as a crucial scientific tool with its powerful ability to decipher cellular and molecular landscapes at single-cell resolution.It is of great significance in solving scientific problems such as the cell classification,intercellular interactions,intercellular communication connections,and the mining of key reproductive genes in animal reproduction.This invaluable technique greatly contributes to advancing our understanding of reproductive mechanisms and enhancing animal reproductive performance.The authors briefly introduce the principles of single-cell sequencing and three types of sequencing,and summarize its role in animal reproductive physiology research,aiming to provide theoretical basis for future research endeavors.关键词
单细胞测序/动物繁殖/细胞分类/细胞通讯/基因挖掘Key words
single-cell sequencing/animal reproductive/cell classification/intercellular communication/gene mining分类
农业科技引用本文复制引用
林广,毛帅翔,柳广斌..单细胞测序及其在动物繁殖机理研究中的作用[J].中国畜牧兽医,2024,51(5):1979-1987,9.基金项目
广东省林业科技创新项目(2023KJCX004) （2023KJCX004）
广东省南方现代草牧业(羊)创新团队(2023KJ127) （羊）
广东省农业农村厅项目(2022-XPY-00-009) （2022-XPY-00-009）
韶关市仁化县牛羊产业园项目(GDSCYY2021-018) （GDSCYY2021-018）
