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慢性肝衰竭并发播散性隐球菌病1例OACSTPCD

A case of chronic liver failure complicated with disseminated cryptococcosis

中文摘要英文摘要

慢性肝衰竭患者由于机体吞噬功能受损、补体水平降低、免疫调节障碍、进行侵入性手术、使用皮质类固醇和抗生素以及与肝脏疾病相关的胃肠道出血等,导致隐球菌感染率明显上升.并发隐球菌感染的肝衰竭患者病情进展迅速,病死率极高.本研究报道了 1例慢性肝衰竭合并播散性隐球菌病的患者,旨在提高临床医生的认识,早诊断,早治疗,提高肝衰竭患者生存率.

Patients with chronic liver failure have significantly increased the incidence of cryptococcal infection due to im-paired phagocytic function,decreased complement levels,immune regulation disorders,invasive surgery,use of corticoste-roids and antibiotics,and gastrointestinal bleeding related to liver diseases.Patients with liver failure complicated with cryp-tococcal infection progress rapidly and have a high mortality rate.This study reported a patient with chronic liver failure complicated with disseminated cryptococcosis,aiming to improve the clinical understanding.

朱紫衣;贺腊;杨晓悦;李毓龙;周利;冀承杰

简阳市人民医院实验医学科,简阳 641400

临床医学

播散性隐球菌病慢性肝衰竭诊断治疗

disseminated cryptococcosischronic liver failurediagnosistreatment

《中国真菌学杂志》 2024 (001)

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四川省科技厅重点研发项目第二版(2022YF50335);成都市医学科研课题(2023564,2022128);简阳市人民医院科研课题(JY202307)

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