中华灾害救援医学2024,Vol.11Issue(2):156-159,4.DOI:10.13919/j.issn.2095-6274.J202403035
罗沙司他对腹膜透析合并贫血患者贫血指标和铁代谢指标的影响
The Effect of Rosuvastatin on Anemia Indicators and Iron Metabolism Indicators in Peritoneal Dialysis Patients with Anemia
祖燕平1
作者信息
- 1. 350000 福建福州,福建省立医院(南院)肾内科
- 折叠
摘要
Abstract
Objective To explore the effects of rosuvastatin on anemia and iron metabolism indicators of patients with peritoneal dialysis(PD)complicated with renal anemia(RA).Methods 94 patients with PD combined with RA were randomly divided into the control group(47)and the rosuvastatin group(47).They were treated with erythropoietin injection and rosuvastatin capsules,respectively,for 12 weeks.We compared the differences in various indicators and therapeutic effects between the two groups before and after treatment,and conduct statistical analysis on adverse reactions.Results Compared with the control group,the total effective rate of treatment in the rosuvastatin group was higher(P<0.05).After treatment,the levels of Hb,RBC,and Hct were higher in the rosuvastatin group compared to the control group(P<0.05).After treatment,compared to the control group,the rosuvastatin group had lower levels of ferritin(P<0.05)and higher levels of transferrin and TAST(P<0.05).The incidence of adverse reactions in the rosuvastatin group was 6.38%,which was significantly lower compared to the control group's 21.28%(P<0.05).Conclusion Rosuvastatin can effectively correct anemia indicators and improve iron metabolism of patients with PD complicated with RA,and its efficacy and safety are better than those of erythropoietin injection.关键词
腹膜透析/贫血/罗沙司他/铁代谢障碍Key words
peritoneal dialysis/anemia/rosasta/iron metabolism disorders分类
医药卫生引用本文复制引用
祖燕平..罗沙司他对腹膜透析合并贫血患者贫血指标和铁代谢指标的影响[J].中华灾害救援医学,2024,11(2):156-159,4.