摘要
Abstract
Objective To investigate the analgesic effect of general anesthesia combined with thoracic paravertebral nerve block(TPVB)and intraoperative analgesic dosage on patients undergoing thoracoscopic surgery.Methods 60 patients who underwent thoracoscopic surgery in our hospital from February to October 2022 were selected and divided into two groups according to the random number table method,with 30 cases in each group.The control group was treated with general anesthesia alone,and the observation group was treated with general anesthesia combined with TPVB.The intraoperative analgesic dosage,body stress indicators before and after surgery,pain degree at different time points after surgery,and postoperative recovery related indicators were compared between the two groups.Results The intraoperative remifentanil dosage in the observation group was(1.82±0.42)mg less than(3.52±1.01)Mg in the control group(t=7.010,P＜0.001).Three days after operation,the detection values of serum norepinephrine(NE),cortisol(COR),and serum substance P(SP)in the observation group were lower than those in the control group(t=2.966,P=0.004;t=3.017,P=0.003;t=2.695,P=0.009).The scores of digital pain assessment scale(NRS)in the observation group at 2h,6h and 12h after operation were lower than those in the control group(t=4.047,P＜0.001;t=3.517,P＜0.001;t=2.132,P=0.037).The postoperative recovery index(extubation,first ambulation,and hospitalization)time of the observation group was shorter than that of the control group(t=6.056,P＜0.001;t=4.840,P＜0.001;t=2.387,P=0.020).Conclusion General anesthesia combined with TPVB can reduce the amount of intraoperative analgesics,reduce the body stress reaction,reduce the degree of postoperative pain,and accelerate the postoperative recovery of patients with thoracoscopic surgery.关键词
麻醉/胸椎/镇痛Key words
anesthesia/thoracic vertebrae/analgesia分类
医药卫生
