中国听力语言康复科学杂志2024，Vol.22Issue(3)：259-263,274,6.DOI:10.3969/j.issn.1672-4933.2024.03.009
平均听阈正常的听神经瘤患者临床及听力学特征分析
The Clinical and Audiological Characteristics of Auditory Neuroma Patients with Normal Mean Auditory Threshold
摘要
Abstract
Objective The clinical and audiological characteristics of unilateral acoustic neuroma patients with normal mean auditory threshold(PTA≤25 dB HL)were analyzed to provide reference for early screening and diagnosis of acoustic neuroma.Methods Thirty-two patients with unilateral acoustic neuroma with normal mean hearing threshold(32 ears)were selected as the experimental group to analyze their clinical and audiological characteristics.A total of 20 patients(32 ears)with normal average hearing threshold matching with age and genders were selected as the control group.Results Tinnitus only,tinnitus accompanied by recurrent and curable sudden hearing loss were the most common initial symptoms in patients with normal auditory threshold auditory neuroma,accounting for 50.00%,most common in people aged 30-40 years old.The abnormal rate of auditory brainstem response was 75.00%(24/32),the abnormal rate of distortion product otoacoustic emission was 78.12%(25/32),the abnormal rates of ipsilomedapedus sound in the affected ear and the abnormal cross acoustic stapedius reflex in the healthy ear were 28.13%and 56.25%,respectively.The abnormal rates of ipsilomedapedial sound in healthy ear and cross acoustic stapedius reflex in affected ear were 6.25%and 62.50%,respectively.The audiological characteristics of the experimental and the control groups were compared and analyzed.For the Wave Ⅲ latency,Wave Ⅴ latency,Wave Ⅰ-Ⅲ interphase and Wave Ⅰ-Ⅴ interphase of auditory brainstem response in the two groups,the cross acoustic stapedius reflex of the affected ear and the healthy ear(0.5,1,2,4 kHz),and the ipsilateral acoustic stapedius reflex of the affected ear(2 kHz),there was a statistical difference between the two groups(P<0.05),and no statistical difference was found in the abnormal rate of distortion product otoacoustic emission between the two groups(P>0.05).Conclusion Auditory brainstem response and acoustic stapedius reflex detection are helpful for the early diagnosis of acoustic neuroma,while distortion product otoacoustic emission is a highly sensitive but poorly specific detection index.For patients with unilateral tinnitus with normal mean hearing threshold in outpatient clinics,or with recurrent and curable sudden hearing loss,it is recommended to use auditory brainstem response,acoustic stapedius reflex,distortion product otoacoustic emission comprehensive assessment to provide basis for early diagnosis of acoustic neuroma.关键词
听神经瘤/纯音听阈正常/听性脑干反应/镫骨肌声反射Key words
Acoustic neuroma/Normal mean auditory threshold/Auditory brainstem response/Acoustic stapedius reflex分类
医药卫生引用本文复制引用
郑秋晨,张秋静,范佳琳,吴谢东,张阳,兰兰,王国建,王秋菊,韩东一..平均听阈正常的听神经瘤患者临床及听力学特征分析[J].中国听力语言康复科学杂志,2024,22(3):259-263,274,6.基金项目
国家自然科学基金项目(82371136) （82371136）
国家自然科学基金项目(82171155) （82171155）
国家重点研发计划项目(2023YFF1203503) （2023YFF1203503）
国家耳鼻咽喉疾病临床医学研究中心开放课题(202200011) （202200011）
