中南大学学报(自然科学版)2024,Vol.55Issue(4):1351-1360,10.DOI:10.11817/j.issn.1672-7207.2024.04.010
无脉冲微流控片上蠕动微泵研制及其性能研究
Development and performance research on pulse-free microfluidic on-chip peristaltic micropump
摘要
Abstract
In order to solve the problems of flow pulse and low accuracy of microfluids in the delivery process,an on-chip peristaltic micropump based on the microfluidic technology was developed.The micropump was composed of a microfluidic chip and a motor actuation system,and the roller bearings on the actuation system were used to press the microchannel of the chip consistently,so as to realize precise fluid delivery.To study the flow performance of the micropump,the microchannel with the air chamber of flow stabilization was designed,and the prototype of microfluidic chip was fabricated by stereo lithography 3D printing technology and molding method.The motor actuation system was developed,and the average flow rate,the total flow rate and the instantaneous flow rate of the micropump under different motor rotational speeds were measured.The flow performance of the proposed micropump was compared with that of a commercial peristaltic pump.The results show that with the increase of the motor rotational speed of the micropump,the average flow rate of the micropump also increases,while the instantaneous flow variation decreases gradually.When the rotational speed of the motor is higher than 60 r/min,the instantaneous flow variation can be controlled within 5%,and the flow precision of the micropump is significantly higher than that of the commercial peristaltic pump.The proposed on-chip peristaltic pump can effectively eliminate the flow pulse and improve the control precision of microfluid,which has vast engineering application prospects in the delivery of precise microfluids.关键词
微流控/片上蠕动微泵/无脉冲/气腔稳流/光固化3D打印Key words
microfluidic/on-chip peristaltic micropump/pulse-free/air chamber for flow stabilization/stereo lithography 3D printing分类
机械制造引用本文复制引用
张鑫杰,包洋,刘宇洋,朱行杰,陈亚伟..无脉冲微流控片上蠕动微泵研制及其性能研究[J].中南大学学报(自然科学版),2024,55(4):1351-1360,10.基金项目
国家自然科学基金资助项目(51905150) (51905150)
中央高校基本科研业务费资助项目(B220202024) (B220202024)
常州市科技计划项目(CE20225046) (CE20225046)
江苏省研究生科研与实践创新计划项目(SJCX22_0169)(Project(51905150)supported by the National Natural Science Foundation of China (SJCX22_0169)
Project(B220202024)supported by the Fundamental Research Funds for the Central Universities (B220202024)
Project(CE20225046)supported by the Changzhou Science and Technology Bureau Program (CE20225046)
Project(SJCX22_0169)supported by the Postgraduate Research&Practice Innovation Program of Jiangsu Province) (SJCX22_0169)