中国现代医生2024，Vol.62Issue(13)：25-28,4.DOI:10.3969/j.issn.1673-9701.2024.13.007
急性胆管炎患者的致病微生物和相关临床特征分析
Analysis of pathogenic microorganisms and related clinical features in patients with acute cholangitis
郝素平 1顾蓓青 1郝建宏2
作者信息
- 1. 海宁市人民医院检验科,浙江海宁 314400
- 2. 海宁市人民医院肝胆外科,浙江海宁 314400
- 折叠
摘要
Abstract
Objective To analyze pathogenic microorganisms and related clinical features in patients with acute cholangitis.Methods The pathogenic microorganism culture results and related clinical data of 229 patients with acute cholangitis in People's Hospital of Haining from 2019 to 2022 were collected and analyzed.Results Among 229 patients,160(69.87%)patients were positive in bile culture,of which 58 patients were infected with multiple bacteria.A total of 227 strains of pathogenic bacteria were isolated from 160 positive bile specimens,of which 136(59.91%)strains were Gram-negative,79(34.80%)strains were Gram-positive and 12(5.29%)strains were fungi.Escherichia coli mixed with Enterococcus faecium was the most common infection(10/58,17.24%).The susceptibility rate of Gram-negative bacteria to amikacin and tigecycline was the highest,and Gram-positive bacteria were highly sensitive to linezolid,vancomycin and tigecycline.Previous biliary surgery history and cirrhosis were independent risk factors for biliary tract infection(P<0.05).Cirrhosis was an independent risk factor for co-infection(P<0.05).Conclusion The pathogenic microorganisms of acute cholangitis are complex in distribution and have some resistance to common antibiotics.Clinicians should pay close attention to patients with acute cholangitis who have a history of biliary tract surgery,cirrhosis and chronic renal insufficiency,and rationally select initial antibiotics.关键词
急性胆管炎/致病微生物/抗菌药物/临床特征Key words
Acute cholangitis/Pathogenic microorganisms/Antibacterial agents/Clinical characteristics分类
医药卫生引用本文复制引用
郝素平,顾蓓青,郝建宏..急性胆管炎患者的致病微生物和相关临床特征分析[J].中国现代医生,2024,62(13):25-28,4.
