中外医学研究2024，Vol.22Issue(11)：139-142,4.DOI:10.14033/j.cnki.cfmr.2024.11.035
腔隙性脑梗死患者认知功能障碍与颅脑MRI显示脑白质变化的关系
Relationship between Cognitive Dysfunction and Brain White Matter Changes Displayed on Brain MRI in Patients with Lacunar Cerebral Infarction
摘要
Abstract
Objective:To analyze the relationship between cognitive dysfunction and brain white matter changes displayed on brain magnetic resonance imaging(MRI)in patients with lacunar cerebral infarction.Method:A total of 98 patients with lacunar cerebral infarction who admitted to Jiangbin Hospital of Guangxi Zhuang Autonomous Region from January 2021 to December 2023 were selected as the study subjects,all patients were given MRI examination,and their cognitive function were evaluated using the mini mental state examination(MMSE)and Montreal cognitive assessment scale(MoCA).Based on the MRI examination results,the patients were grouped,and the clinical data of different groups were compared,Spearman correlation analysis was used to analyze the relationship between MRI white matter changes in lacunar infarction and the above scale scores.Result:A total of 98 patients were examined by MRI,according to the grading standard of white matter lesions,19 cases of grade 0(grade 0 group),26 cases of grade 1(grade 1 group),30 cases of grade 2(grade 2 group),23 cases of grade 3(grade 3 group).There were no significant differences in clinical data among four groups(P>0.05).There were significant differences in MMSE score and MoCA score among four groups(P<0.05).Spearman correlation analysis showed that the degree of white matter lesions in patients with lacunar infarction was negatively correlated with MMSE score and MoCA score(r=-0.823,-0.808,P<0.05).Conclusion:Cognitive dysfunction in patients with lacunar cerebral infarction is related to white matter lesions,related cognitive function scores are negatively correlated with the severity of white matter lesions,clinically,cognitive impairment can be estimated based on white matter lesions.关键词
腔隙性脑梗死/认知功能障碍/磁共振成像/脑白质变化/简明精神状态检查量表/蒙特利尔认知功能评估量表Key words
Lacunar cerebral infarction/Cognitive dysfunction/Magnetic resonance imaging/Brain white matter change/Mini mental state examination scale/Montreal cognitive assessment scale引用本文复制引用
叶彬,梁春荣,卢慧娟,王钊,石慧铃,郭家俊..腔隙性脑梗死患者认知功能障碍与颅脑MRI显示脑白质变化的关系[J].中外医学研究,2024,22(11):139-142,4.基金项目
广西壮族自治区卫健委自筹经费科研课题项目(Z20200634) （Z20200634）
