中外医学研究2024，Vol.22Issue(11)：147-150,4.DOI:10.14033/j.cnki.cfmr.2024.11.037
外周血PTH、CRP表达水平对缺血性脑卒中患者预后的评估价值
Evaluation Value of Peripheral Blood PTH and CRP for Prognosis of Patients with Ischemic Stroke
邓艳梅1
作者信息
- 1. 北京市丰台中西医结合医院 北京 100072
- 折叠
摘要
Abstract
Objective:To explore the value of peripheral blood parathyroid hormone(PTH)and C-reactive protein(CRP)expression levels in prognosis assessment of patients with ischemic stroke.Method:A total of 116 patients with ischemic stroke admitted to Beijing Fengtai Hospital of Integrated Chinese and Western Medicine from June 2018 to December 2021 were selected as the study objects.According to the infarct size,they were divided into mild group(n=49),moderate group(n=44)and severe group(n=23),and peripheral blood PTH and CRP levels of patients with different severity were compared.The correlation with infarct size was analyzed.The patients were divided into good prognosis group(n=91)and poor prognosis group(n=25)according to the modified Rankin scale(mRS)score at 3 months after the onset of the disease.The predictive value of peripheral blood PTH and CRP levels on the prognosis of patients and their relationship with the occurrence of poor prognosis were analyzed.Result:The levels of PHT and CRP in moderate group and severe group were higher than those in mild group,and the levels of PHT and CRP in severe group were higher than those in moderate group,the differences were statistically significant(P<0.05).The levels of PTH and CRP in peripheral blood were positively correlated with the infarct size of patients with ischemic stroke(P<0.05).The levels of PTH and CRP in peripheral blood of poor prognosis group were higher than those of good prognosis group,and the differences were statistically significant(P<0.05).The area under curve(AUC)of combined detection of PTH and CRP levels in peripheral blood predicted the prognosis of patients was greater than that of PTH and CRP alone,the difference was statistically significant(P<0.05).PTH≥12.82 ng/L and CRP≥8.16 mg/L were the influencing factors leading to adverse prognosis in patients with ischemic stroke(P<0.05).Conclusion:The levels of PTH and CRP in peripheral blood of patients with ischemic stroke are correlated with the infarct size,and the combined detection of these two levels is valuable to evaluate the prognosis of patients.关键词
甲状旁腺激素/C反应蛋白/缺血性脑卒中/预后/评估价值Key words
Parathyroid hormone/C-reactive protein/Ischemic stroke/Prognosis/Evaluation value引用本文复制引用
邓艳梅..外周血PTH、CRP表达水平对缺血性脑卒中患者预后的评估价值[J].中外医学研究,2024,22(11):147-150,4.
