中华临床免疫和变态反应杂志2024，Vol.18Issue(2)：105-109,5.DOI:10.3969∕j.issn.1673-8705.2024.02.001
对嗜酸性肉芽肿性多血管炎临床诊断与治疗的思考
Clinical challenges in the diagnosis and treatment of eosinophilic granulomatosis with polyangiits
摘要
Abstract
Eosinophilic granulomatosis with polyangiitis(EGPA)is characterized by an increase in eo-sinophils,the formation of granulomas,and necrotizing vasculitis in small to medium-sized blood ves-sels.EGPA patients experience organ damage due to infiltration of eosinophils,fibrosis induced by eosinophils,and a hypercoagulable state,accompanied by allergic manifestations.This article provides a comprehensive re-view of the pathogenesis,clinical presentation,changes in classification criteria,and advances in treatment for EGPA.Additionally,suggestions and considerations are proposed regarding the clinical challenges in diag-nosing and treating EGPA.关键词
血管炎/嗜酸细胞增多/生物制剂Key words
vasculitis/eosinophilia/biologics引用本文复制引用
施举红..对嗜酸性肉芽肿性多血管炎临床诊断与治疗的思考[J].中华临床免疫和变态反应杂志,2024,18(2):105-109,5.基金项目
国家重点研发计划常见多发病防治研究(2023YFC2507204) （2023YFC2507204）
中央高水平医院临床科研业务费(2022-PUMCH-C-017) National Key R&D Program of China(2023YFC2507204) （2022-PUMCH-C-017）
National High Level Hos-pital Clinical Research Funding(2022-PUMCH-C-017) （2022-PUMCH-C-017）
