中华临床免疫和变态反应杂志2024,Vol.18Issue(2):164-168,5.DOI:10.3969∕j.issn.1673-8705.2024.02.009
糖代谢在类风湿关节炎发病中的作用
Role of glucose metabolism in the pathogenesis of rheumatoid arthritis
马向波 1李镕利 2吴逊尧 2费允云2
作者信息
- 1. 056002 河北邯郸,邯郸市第一医院风湿免疫科||100730 北京,中国医学科学院 北京协和医学院 北京协和医院风湿免疫科
- 2. 100730 北京,中国医学科学院 北京协和医学院 北京协和医院风湿免疫科
- 折叠
摘要
Abstract
Rheumatoid arthritis(RA)is a systemic inflammatory autoimmune disease characterized by chronic,symmetrical,destructive multijoint synovitis.Immune system disorders and inflammation play an im-portant role in its pathogenesis.In recent years,some studies have shown that glucose metabolism is involved in the abnormal activation of immune cells and the inflammatory reaction process,which is closely related to the pathogenesis of RA.Therefore,this paper reviews the relationship between glucose metabolism and T cells,B cells,macrophages,inflammation and insulin resistance in RA,as well as its role in pathogenesis.It may pro-vides a new idea for the treatment of RA.关键词
类风湿关节炎/糖代谢/T细胞/B细胞/巨噬细胞/炎症/胰岛素抵抗Key words
rheumatoid arthritis/glucose metabolism/T lymphocytes/B lymphocytes/macrophage/inflammation/insulin resistance引用本文复制引用
马向波,李镕利,吴逊尧,费允云..糖代谢在类风湿关节炎发病中的作用[J].中华临床免疫和变态反应杂志,2024,18(2):164-168,5.