中华灾害救援医学2024，Vol.11Issue(2)：138-141,4.DOI:10.13919/j.issn.2095-6274.J202402047
妊娠合并亚临床甲状腺功能减退症与早产的相关性分析
Correlation Analysis between Subclinical Hypothyroidism during Pregnancy and Preterm Birth
摘要
Abstract
Objective To analyze the incidence of subclinical hypothyroidism(abbreviated as hypothyroidism)during pregnancy in pregnant women,and to analyze the correlation between this disease and preterm birth.Methods Using a retrospective research method,pregnant women admitted to Jinjiang Hospital from February 2021 to June 2023 were selected as the study subjects.Clinical symptoms,laboratory examination results,and imaging examination results of the study subjects were collected and organized.Finally,82 patients with gestational hypothyroidism were included in the observation group,and 118 healthy pregnant women without gestational hypothyroidism were included in the control group.We analyze the risk factors for inducing hypothyroidism during pregnancy and the correlation between this disease and preterm birth.Results Univariate analysis showed that there were statistically significant differences between the observation group and the control group in smoking or long-term smoking environment,pregnancy hypertension,placental abruption,premature rupture of membranes,abnormal BMI,history of abortion,gestational diabetes,fetal growth restriction,Hb,TSH,TPOAb,TRAb,and pregnancy outcomes(P＜0.05).Logistic regression analysis showed that diabetes in pregnancy,pregnancy hypertension,smoking or long-term smoking environment,placental abruption,premature rupture of membranes,abnormal BMI,abortion history,fetal growth restriction,Hb＜110g/L,TSH＞3.0mIU/L,TPOAb＞34IU/ml,TRAb＞1.71IU/L were the high-risk factors leading to hypothyroidism in pregnant women(P=0.000).Pearson program analysis shows that preterm birth is negatively correlated with Hb,while preterm birth is positively correlated with TSH,TPOAb,and TRAb.Conclusion Clinical hypothyroidism is closely related to the pregnancy outcome.In order to effectively prevent this problem,we need to strengthen the control of serological indicators such as hypertension,diabetes,TSH,in order to avoid affecting the pregnancy outcome.关键词
甲状腺功能减退症/妊娠结局/早产Key words
hypothyroidism/pregnancy outcome/premature birth分类
医药卫生引用本文复制引用
施冬华,倪婧玲..妊娠合并亚临床甲状腺功能减退症与早产的相关性分析[J].中华灾害救援医学,2024,11(2):138-141,4.基金项目
第二批泉州市高层次人才创新创业项目(2023C014YR) （2023C014YR）
