神经药理学报2024，Vol.14Issue(1)：49-56,8.DOI:10.3969/j.issn.2095-1396.2024.01.009
神经活性类固醇抗抑郁作用研究进展
Research Progress of Neuroactive Steroid in the Treatment of Depression
摘要
Abstract
Depression is a chronic syndrome with complex etiology.Nearly one-third of patients are not sensitive to current antidepressants.In order to ensure the quality of life of all patients with depression,it is essential to explore new antidepressant treatment methods.Neuroactive steroids are metabolites of steroid hormones play an antidepressant role through multiple pathways and multiple targets.In this paper,the literature on neuroactive steroids in the treatment of depression was summarized to provide scientific basis for neuroactive steroids in the treatment of depression,and to provide new ideas for the development of antidepressant drugs.关键词
神经活性类固醇/抑郁症/机制Key words
neuroactive steroid/depression/mechanism分类
医药卫生引用本文复制引用
张冉冉,吴志刚..神经活性类固醇抗抑郁作用研究进展[J].神经药理学报,2024,14(1):49-56,8.基金项目
河北省省属高校基本科研业务费自然科学研究计划项目(No.JYT2021001),河北北方学院校级科研项目(No.XJ2023034),河北北方学院博士科研启动基金项目资助 （No.JYT2021001）
