多指标结合AHP-CRITIC优化酸枣叶拌蒸酸枣仁炮制工艺OACSTPCD
Optimization of the Co-steaming Process of Semen Ziziphi Spinosae with Ziziphus Jujuba Leaf by Multi-index Combined with AHP-CRITIC Method
目的:采用正交设计结合层次分析法-客观赋权法(AHP-CRITIC)优化酸枣叶拌蒸酸枣仁的炮制工艺.方法:采用单因素试验优化辅料酸枣叶的加入倍量和蒸制时间,以酸枣叶的加入倍量和蒸制时间为因素,以斯皮诺素、6‴-阿魏酰斯皮诺素、酸枣仁皂苷A、白桦脂酸含量为评价指标进行综合加权评分,结合AHP-CRITIC优化酸枣仁的拌蒸工艺.结果:最佳拌蒸工艺为酸枣叶加入量是酸枣仁的4倍,1层酸枣叶1层酸枣仁交替平铺,上锅蒸制3 h.结论:多指标结合AHP-CRITIC优选酸枣仁拌蒸工艺合理可行,可为酸枣叶拌蒸酸枣仁炮制工艺的生产实践提供参考.
Objective:To optimize the co-steaming process of Semen ziziphi spinosae with Ziziphus jujuba leaf based on orthogonal design and AHP-CRITIC method.Method:The single-factor experiment was applied to screen dosage range for Z.jujuba leaf and steaming time.Then,the co-steaming process was optimized by orthogonal design combined with AHP-CRITIC method with the contents of spinosin,6‴-ferulospinosin,jujuboside A,and betulinic acid as evaluation indexes and usage amount of Z.jujuba leaf and steaming time as influencing factors.Results:The optimal co-steaming process was to lay the Z.jujuba leaf and Semen ziziphi spinosae alternately,and the usage amount for Z.jujuba leaf was four times that of Semen ziziphi spinosae.The steaming time was 3 hours.Conclusion:The orthogonal design combined with AHP-CRITIC method was reasonable and feasible,and could provide a reference for the production practice of co-steaming process of Semen ziziphi spinosae with Z.jujuba leaf.
程世赞;华悦;廉婧;聂紫璇;苏国明;常源;史辑;贾天柱
辽宁中医药大学 药学院,辽宁 大连 116600辽宁中医药大学 药学院,辽宁 大连 116600||辽宁省中药炮制技术产业创新中心,辽宁 大连 116600
中医学
酸枣仁酸枣叶拌蒸工艺正交设计层次分析法-客观赋权法
Semen ziziphi spinosaeZiziphus jujuba leafco-steaming processorthogonal designAHP-CRITIC
《中国现代中药》 2024 (004)
677-684 / 8
国家自然科学基金项目(81874345);国家中医药管理局重点实验室研究领域的中医临床疗效提升项目(2100222179);沈阳市中青年科技创新人才支持计划项目(RC200174);2022年辽宁省自然科学基金资助面上项目(2022-MS-223)
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