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Establishment of human cerebral organoid systems to model early neural development and assess the central neurotoxicity of environmental toxins

Daiyu Hu Yuanqing Cao Chenglin Cai Guangming Wang Min Zhou Luying Peng Yantao Fan Qiong Lai Zhengliang Gao

Neural Regeneration Research2025,Vol.20Issue(1):P.242-252,11.
Neural Regeneration Research2025,Vol.20Issue(1):P.242-252,11.DOI:10.4103/NRR.NRR-D-23-00928

Establishment of human cerebral organoid systems to model early neural development and assess the central neurotoxicity of environmental toxins

Daiyu Hu 1Yuanqing Cao 1Chenglin Cai 2Guangming Wang 2Min Zhou 3Luying Peng 4Yantao Fan 5Qiong Lai 3Zhengliang Gao5

作者信息

  • 1. Fundamental Research Center,Shanghai Yangzhi Rehabilitation Hospital(Shanghai Sunshine Rehabilitation Center),School of Medicine,Tongji University,Shanghai,China Institute of Geriatrics(Shanghai University),Affiliated Nantong Hospital of Shanghai University(The Sixth People’s Hospital of Nantong),Shanghai University School of Medicine,Nantong,Jiangsu Province,China Shanghai Engineering Research Center of Organ Repair,Shanghai University School of Medicine,Shanghai,China Key Laboratory of Arrhythmias,Ministry of Education,Shanghai East Hospital,School of Medicine,Tongji University,Shanghai,China
  • 2. Fundamental Research Center,Shanghai Yangzhi Rehabilitation Hospital(Shanghai Sunshine Rehabilitation Center),School of Medicine,Tongji University,Shanghai,China Key Laboratory of Arrhythmias,Ministry of Education,Shanghai East Hospital,School of Medicine,Tongji University,Shanghai,China
  • 3. Institute of Geriatrics(Shanghai University),Affiliated Nantong Hospital of Shanghai University(The Sixth People’s Hospital of Nantong),Shanghai University School of Medicine,Nantong,Jiangsu Province,China Shanghai Engineering Research Center of Organ Repair,Shanghai University School of Medicine,Shanghai,China
  • 4. Key Laboratory of Arrhythmias,Ministry of Education,Shanghai East Hospital,School of Medicine,Tongji University,Shanghai,China
  • 5. Fundamental Research Center,Shanghai Yangzhi Rehabilitation Hospital(Shanghai Sunshine Rehabilitation Center),School of Medicine,Tongji University,Shanghai,China Institute of Geriatrics(Shanghai University),Affiliated Nantong Hospital of Shanghai University(The Sixth People’s Hospital of Nantong),Shanghai University School of Medicine,Nantong,Jiangsu Province,China Shanghai Engineering Research Center of Organ Repair,Shanghai University School of Medicine,Shanghai,China
  • 折叠

摘要

关键词

cadmium/cell death/cell proliferation/cortical development/environmental toxins/neural progenitor cells/neurogenesis/neurotoxicology/organoids/stem cells

分类

医药卫生

引用本文复制引用

Daiyu Hu,Yuanqing Cao,Chenglin Cai,Guangming Wang,Min Zhou,Luying Peng,Yantao Fan,Qiong Lai,Zhengliang Gao..Establishment of human cerebral organoid systems to model early neural development and assess the central neurotoxicity of environmental toxins[J].Neural Regeneration Research,2025,20(1):P.242-252,11.

基金项目

supported by the National Key R&D Program of China,No.2019YFA0110300(to ZG) (to ZG)

the National Natural Science Foundation of China,Nos.81773302(to YF),32070862(to ZG). (to YF)

Neural Regeneration Research

1673-5374

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