大学化学2024，Vol.39Issue(4)：395-400,6.DOI:10.3866/PKU.DXHX202310047
基于米氏机理的酶催化反应中反应速率常数的计算
Determination of All Rate Constants in the Enzyme Catalyzed Reactions Based on Michaelis-Menten Mechanism
张恒1
作者信息
- 1. 武汉大学化学与分子科学学院,武汉 430072
- 折叠
摘要
Abstract
Two protocols,the transient method and the mathematical method,are introduced to deduce all the rate constants in the enzyme-catalyzed reaction model based on the Michaelis-Menten mechanism.The transient method focuses on analyzing the period before reaching a steady state,while the mathematical method aims to establish a relationship between the concentration of the enzyme and the substrate.By calculating all the rate constants,one can enhance their understanding and grasp of the kinetics of the enzyme-catalyzed reaction.关键词
酶催化反应/动力学/米氏机理/速率常数Key words
Enzyme catalyzed reaction/Kinetics/Michaelis-Menten mechanism/Rate constant分类
社会科学引用本文复制引用
张恒..基于米氏机理的酶催化反应中反应速率常数的计算[J].大学化学,2024,39(4):395-400,6.
