基础医学与临床2024，Vol.44Issue(6)：840-844,5.DOI:10.16352/j.issn.1001-6325.2024.06.0840
臭氧联合低温等离子射频消融术对神经根型颈椎病的疗效
Efficacy of ozone combined with low temperature plasma radiofrequency ablation in the treatment of cervical spondylotic radiculopathy
摘要
Abstract
Objective To investigate the therapeutic effectiveness of ozone combined with low-temperature plasma coagulation therapy on patients with cervical spondylotic radiculopathy and its influence on inflammatory responses.Methods Ozone in combination with low-temperature plasma radio-frequency coagulation was applied to 75 patients with cervical spondylotic radiculopathy in Pain Medicine Department of Capital Medical University Affiliated Beijing Anzhen Hospital from May 2022 to May 2023.Pain scores were assessed using Visual Analog Scale(VAS)and Neck Disability Index(NDI)before and two weeks after treatment.Enzyme-linked immunosor-bent assay(ELISA)was used to analyze the level of tumor necrosis factor-alpha(TNF-α),interleukin-6(IL-6)and interferon-gamma(IFN-γ)before and two weeks after treatment.Results After treatment with ozone plus low-temperature plasma radiofrequency,VAS and NDI scores showed a significant decrease[VAS:5.36(4,7)vs.1.32(1,2),P＜0.000 1;NDI:32.72(24,70)vs.7.62(3.55,8.9),P＜0.000 1].Two weeks after surgical intervention,there was an effective reduction in the level of IL-6,TNF-αand IFN-γ alleviating the inflammatory re-sponse[IL-6:4.33(2.51,5.04)vs.3.49(2.08,4.43),P＜0.05;TNF-α:1.95(1.41,2.21)vs.1.61(1.02,2.03),P＜0.05;IFN-γ:1.84(1.18,2.47)vs.1.55(0.76,2.09),P＜0.05].Conclusions This Ozone combined with low-temperature plasma radiofrequency ablation is an effective technology for treatment of cer-vical spondylotic radiculopathy.关键词
神经根型颈椎病/臭氧/低温等离子射频消融术/炎性反应Key words
cervical spondylotic radiculopathy/ozone/low-temperature plasma radiofrequency ablation/inflammatory response分类
医药卫生引用本文复制引用
霍岩松,孙海燕,庞金磊,郭向飞,刘亚静,冉广原,何明伟..臭氧联合低温等离子射频消融术对神经根型颈椎病的疗效[J].基础医学与临床,2024,44(6):840-844,5.基金项目
国家自然科学基金(61875141) （61875141）
