原发性乳腺淋巴瘤误诊误治分析OACSTPCD

Objective To investigate the clinical manifestations,causes of misdiagnosis and preventive measures of primary breast lymphoma(PBL).Methods The clinical data of 3 patients with PBL misdiagnosed as breast cancer were an-alyzed retrospectively.Results All the 3 patients presented with breast mass as the first symptom,and were initially misdiag-nosed as breast cancer.The duration of misdiagnosis was 9-31 d.Two patients underwent modified radical mastectomy and one underwent unilateral mastectomy plus sentinel lymph node biopsy.All 3 patients were diagnosed with PBL by pathological and immunohistochemical examination,and were given chemotherapy and radiotherapy after surgery.During follow-up to date,1 case died after recurrence more than 3 years after surgery,and 2 cases had no recurrence.Conclusion The incidence of PBL is very low,and the lack of specific clinical manifestations and related medical tests may lead to misdiagnosis.During clinical encounters with patients similar to those described in this study,PBL should be taken into account,coarse needle puncture or resection biopsy of the tumor should be completed in time,and the condition and differential diagnosis should be carefully ana-lyzed to reduce or avoid misdiagnosis and mistreatment.