西南医科大学学报2024，Vol.47Issue(3)：193-199,7.DOI:10.3969/j.issn.2096-3351.2024.03.003
早产儿支气管肺发育不良相关危险因素的研究与展望
Research and Perspective of risk factors related to bronchopulmonary dysplasia in premature infants
摘要
Abstract
Bronchopulmonary dysplasia(BPD)is the most common chronic respiratory disease in preterm infants,especially in extreme preterm infants.Studies have shown that BPD can negatively affect respiratory health throughout childhood and even after ado-lescence.BPD is a complex multifactorial developmental disease in which a variety of prenatal,intrapartum,and postnatal factors,along with genetic predisposition,contribute to lung damage,remodeling,and repair.With the development of perinatal medicine and the im-provement of the treatment level for critically ill neonates in the neonatal intensive care unit,the survival rate of extremely preterm in-fants has significantly improved,but the incidence of BPD has not decreased.There are currently no effective strategies to prevent or treat BPD.Therefore,early identification of BPD predictors and development of new and reliable BPD prediction models have become the focus of research in recent years.The purpose of this article was to review the latest progress on risk factors related to bronchopulmo-nary dysplasia in preterm infants,aiming to provide a foundation for selecting clinical trial subjects for potential preventive therapy and establishing potential prevention strategies.关键词
早产儿/支气管肺发育不良/危险因素/预测Key words
Premature infants/Bronchopulmonary dysplasia/Risk factor/Projections分类
医药卫生引用本文复制引用
董文斌,何婷,章容..早产儿支气管肺发育不良相关危险因素的研究与展望[J].西南医科大学学报,2024,47(3):193-199,7.基金项目
国家自然科学基金面上项目(82371710 （）
81571480) （）
四川省科技厅重点研发项目(22ZDYF1470) （22ZDYF1470）
泸州市科技计划项目(2022-JYJ-122) （2022-JYJ-122）
