西南医科大学学报2024，Vol.47Issue(3)：226-230,5.DOI:10.3969/j.issn.2096-3351.2024.03.009
儿童重症支原体肺炎风险因素阈值与预测价值
Threshold and predictive values of risk factors for Severe mycoplasma pneu-moniae pneumonia in children
摘要
Abstract
Objective The prevalence of severe mycoplasma pneumoniae pneumonia is increasing,the purpose of this study was to investigate the threshold and predictive value of risk factors for severe mycoplasma pneumonia in children.Methods Retrospective analysis was conducted on 224 children who were hospitalized in the Second Affiliated Hospital of Army Medical University for MPP be-tween January 2023 and February 2024.The children were divided into severe group(114 cases)and non-severe group(110 cases),After comparing the laboratory tests of two groups,logistic stepwise regression analysis was carried out on the statistically significant in-dicators to obtain independent predictive indicators for severe mycoplasma pneumoniae pneumonia,and then,the threshold(cut off)value with the maximum diagnostic value for each predictive indicator was found through the analysis of the receiver operating character-istic curve(ROC).Results The SMPP group had higher levels of CRP,LDH and D-dimer,while PLT was significantly lower than that of the MPP group,and the differences were statistically significant(all P＜0.05),and there were no significant differences in WBC,AST and ALT,with all P＞0.05.Bringing them into univariate logistic regression analysis and multivariate logistic analysis,the results showed that CRP(OR=0.032,P=0.006),LDH(OR=0.006,P=0.044),and D-dimer(OR=0.006,P<0.001),were independent predictors of severe Mycoplasma pneumoniae pneumonia in children.The areas under the ROC curves of CRP,LDH,and D-dimer were 0.732、0.696、0.807,respectively.Cut-offs were 10.35 mg/L,296.15 U/L,and 231.5 ng/ml,respectively.Conclusion CRP≥10.35 mg/L,LDH≥296.15 U/L,D-dimer≥231.5 ng/ml were early independent warning indicators for severe mycoplasma pneumoniae pneumo-nia in children,among which D-dimer showed the greatest diagnostic value.关键词
儿童/重症支原体肺炎/风险因素/阈值/预测价值Key words
Children/Severe mycoplasma pneumoniae pneumonia/Risk factors/Threshold/Predictive value分类
医药卫生引用本文复制引用
胡楠,屈福祥,程旺,颜丽君,杨望..儿童重症支原体肺炎风险因素阈值与预测价值[J].西南医科大学学报,2024,47(3):226-230,5.基金项目
陆军军医大学信息化改革项目(2022018) （2022018）
